426833-34-3

Upstream product

• 179167-09-0 N,N-bis(2-aminoethyl)-N-[2-(N-t-butoxycarbonylamino)ethyl]amine 
• 426833-33-2 N,N-bis[2-(4-methyl(phenylsulfonamido))ethyl]-N-[2-(tert-butylcarbamoyl)ethyl]amine 

Downstream Products

• 1360933-44-3 C₆₅H₅₇N₉O₅S₂Zn 
• 1118431-54-1 C₂₈H₃₄F₃N₅O₆S₂ 
• 1118431-45-0 C₂₈H₃₄F₃N₅O₅S₂ 
• 1118431-44-9 C₂₈H₃₇N₅O₆S₂ 
• 1118431-56-3 C₂₇H₃₄ClN₅O₄S₃ 
• 1118431-59-6 C₂₇H₃₆N₄O₄S₂ 
• 1118431-49-4 C₃₃H₃₉N₅O₆S₂ 
• 1118431-43-8 C₂₇H₃₄ClN₅O₅S₂ 
• 1118431-51-8 C₂₈H₃₄N₆O₅S₂ 
• 1118431-53-0 C₃₁H₄₃N₅O₅S₂ 

Relevant academic research and scientific papers

Facilitated phospholipid translocation in vesicles and nucleated cells using synthetic small molecule scramblases

A series of 16 synthetic scramblase candidates were prepared from a tris(aminoethyl)amine (TREN) scaffold and evaluated for ability to facilitate translocation of fluorescent phospholipid probes across vesicle membranes and endogenous phosphatidylserine a

Facilitated phosphatidylserine flip-flop across vesicle and cell membranes using urea-derived synthetic translocases

Tris(2-aminoethyl)amine derivatives with appended urea and sulfonamide groups are shown to facilitate the translocation of fluorescent phospholipid probes and endogenous phosphatidylserine across vesicle and erythrocyte cell membranes. The synthetic translocases appear to operate by binding to the phospholipid head groups and forming lipophilic supramolecular complexes which diffuse through the non-polar interior of the bilayer membrane.