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426842-85-5

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426842-85-5 Usage

General Description

3-Fluoro-6-methoxyquinoline is a chemical compound with the molecular formula C10H8FNO. It is a quinoline derivative that contains a fluorine atom at the 3-position and a methoxy group at the 6-position. 3-fluoro-6-methoxyquinoline is an aromatic heterocyclic compound, commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical drugs. It has also been studied for its potential biological activities, including its antifungal and antibacterial properties. Additionally, it has been investigated for its potential use in organic synthesis as a reagent or catalyst. Overall, 3-fluoro-6-methoxyquinoline is an important compound with various potential applications in the pharmaceutical, chemical, and biological fields.

Check Digit Verification of cas no

The CAS Registry Mumber 426842-85-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,6,8,4 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 426842-85:
(8*4)+(7*2)+(6*6)+(5*8)+(4*4)+(3*2)+(2*8)+(1*5)=165
165 % 10 = 5
So 426842-85-5 is a valid CAS Registry Number.

426842-85-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Fluoro-6-methoxyquinoline

1.2 Other means of identification

Product number -
Other names Quinoline,3-fluoro-6-methoxy

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:426842-85-5 SDS

426842-85-5Relevant articles and documents

Synthesis of 4-halogenated 3-fluoro-6-methoxyquinolines: Key building blocks for the synthesis of antibiotics

Flagstad, Thomas,Petersen, Mette T.,Hinnerfeldt, Daniel M.,Givskov, Michael,Nielsen, Thomas E.

, p. 3263 - 3267 (2014)

A practical and scalable 4-step route is presented for the synthesis of 4-bromo-3-fluoro-6-methoxyoquinoline and 3-fluoro-4-iodo-6-methoxyoquinoline from readily available 2,4-dichloro-3-fluoroquinoline with an overall yield of 81-85%. Halogenated quinoline building blocks have found much use in antimicrobial drug discovery, and the method reported here would be useful for the synthesis of these compounds.

Initial Route Scouting and Final Process Development for the Multi-Kg Production of 3-Fluoro-6-methoxyquinoline from p-Anisidine and 2-Fluoromalonic Acid

Sch?fer, Gabriel,Fleischer, Tony,Blumer, Nicole,Udry, Megan,Reber, Stefan,Stansfield, Ian,Liu, Yuanhua,Li, Yan,Li, Pixu

, p. 347 - 357 (2022/02/01)

A scalable route to 3-fluoro-6-methoxyquinoline needed to be developed as multi-kg amounts of this heterocycle were required. Initial route development focused on the formation of the key C-F bond via a Balz-Schiemann reaction or electrophilic fluorinatio

Hepatitis C Virus Inhibitors

-

, (2013/05/21)

Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

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