426844-51-1

Basic information

• Product Name: 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE
• Synonyms: 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE;4,4-Difluoro-l-prolinaMide, HCl;(S)-4,4-difluoropyrrolidine-2-carboxamide hydrochloride;-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride
• CAS NO: 426844-51-1
• Molecular Formula: C5H9ClF2N2O
• Molecular Weight: 186.59
• Mol File: 426844-51-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 222°C
• Boiling Point: 327.5ºC at 760 mmHg
• Flash Point: 151.9 ºC
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.000145mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE(426844-51-1)
• EPA Substance Registry System: 4,4-DIFLUORO-L-PROLINAMIDE HYDROCHLORIDE(426844-51-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 426844-51-1(Hazardous Substances Data)

Usage

Uses

4,4-Difluoro-L-prolinamide hydrochloride can be used as a building block in the synthesis of cyanopyrrolidine based DPP-IV inhibitors.

InChI:InChI=1/C5H8F2N2O.ClH/c6-5(7)1-3(4(8)10)9-2-5;/h3,9H,1-2H2,(H2,8,10);1H/t3-;/m0./s1

Downstream Products

• 1448440-48-9 (S)-tert-butyl 2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethylcarbamate