Basic information

Product Name: GEODIN
Synonyms: SPIRO[BENZOFURAN-2(3H),1'-[2,5]CYCLOHEXADIENE]-2'-CARBOXYLIC ACID, 5,7-DICHLORO-4-HYDROXY-6'-METHOXY-6-METHYL-3,4'-DIOXO-, METHYL ESTER;GEODIN;(+)-ESTIN;Estin, (+)-5,7-dichloro-4-hydroxy-6-methoxy-6-methyl-3,4-dioxo-spiro[benzofuran-2(3H),1-[2,5]cyclohexadiene]-2-carboxylic acid methyl ester;(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6-methoxy-6'-methylspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester;(1R)-3',4-Dioxo-4'-hydroxy-5',7'-dichloro-6'-methyl-6-methoxyspiro[2,5-cyclohexadiene-1,2'(3'H)-benzofuran]-2-carboxylic acid methyl ester;(R)-5,7-Dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester;d-Geodin
CAS NO:427-63-4
Molecular Formula: C17H12Cl2O7
Molecular Weight: 399.18
EINECS: N/A
Product Categories: N/A
Mol File: 427-63-4.mol

Chemical Properties

Melting Point: 235℃
Boiling Point: 652.1 °C at 760 mmHg
Flash Point: 348.2 °C
Appearance: /
Density: 1.61 g/cm³
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: GEODIN(CAS DataBase Reference)
NIST Chemistry Reference: GEODIN(427-63-4)
EPA Substance Registry System: GEODIN(427-63-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 427-63-4(Hazardous Substances Data)

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SDS
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427-63-4 Usage

Uses

Used in Pharmaceutical Applications:
GEODIN is used as a therapeutic agent for promoting fibrinolysis and inhibiting plasminogen activator inhibitor (PAI-1). This application is particularly relevant in the treatment of conditions related to impaired fibrinolytic activity, such as thrombotic disorders and cardiovascular diseases.
Used in Research Applications:
GEODIN is used as a research tool for studying the mechanisms underlying fibrinolysis and the role of PAI-1 in various pathological processes. Its ability to increase 2-deoxyglucose uptake by rat adipocytes also makes it a valuable compound for investigating glucose metabolism and its regulation in cellular systems.
Used in Drug Development:
GEODIN's inhibitory effect on PAI-1 and its potential to enhance fibrinolytic activity make it a promising candidate for the development of new drugs targeting thrombotic and cardiovascular disorders. Further research and development efforts may lead to the creation of novel therapeutic agents based on GEODIN's unique properties.

Check Digit Verification of cas no

The CAS Registry Mumber 427-63-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,2 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 427-63:
(5*4)+(4*2)+(3*7)+(2*6)+(1*3)=64
64 % 10 = 4
So 427-63-4 is a valid CAS Registry Number.

427-63-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate

1.2 Other means of identification

Product number	-
Other names	Geodin

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:427-63-4 SDS

427-63-4Upstream product

2151-16-8 methyl 2-(3,5-dichloro-2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoate

427-63-4Downstream Products

102173-59-1 methyl 2,4-dichloroasterrate

427-63-4Relevant academic research and scientific papers

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