42747-23-9Relevant academic research and scientific papers
A Facile Synthesis of 1,2-Divinylcycloalkanols and Their Behavior in the Oxy-Cope Rearrangement
Kato, Tetsuya,Kondo, Hisao,Nishino, Masaki,Tanaka, Minoru,Hata, Go,Miyake, Akihisa
, p. 2958 - 2961 (2007/10/02)
The reaction of 2-chlorocycloalkanones with vinylmagnesium chloride gives 1,2-divinylcycloalkanols.Divinylation proceeds via a rearrangement of initially formed 2-chloro-1-vinylcycloalkanols to 2-vinylcycloalkanones followed by further vinylation of 2-vinylcycloalkanones.Thermal sigmatropic rearrangement of 1,2-divinylcycloalkanols gives 5-cycloalken-1-ones in good yields.The influence of the size of rings on the reaction pathways is discussed.
