42769-13-1Relevant academic research and scientific papers
STEREOCHEMISTRY AT SECONDARY CARBON IN ORGANOMETALLIC INSERTION REACTIONS
Cotton, J. D.,Crisp, G. T.
, p. 137 - 145 (1980)
The stereochemistry of insertion reactions occurring at secondary carbon atoms bound to transition metals has been probed by examination of 13C and 1H spectra of 1,4-disubstituted cyclohexyl systems.The reaction of neat sulfur dioxide with cis and trans -4-methylcyclohexyl (pyridine)-cobaloxime leads to the trans and cis -4-methylcyclohexyl-S-sulfinate cobaloximes respectively, indicating inversion of configuration at the reacting carbon atom.A similar inversion is observed in the reaction of sulfur dioxide with 5-C5H5)>, but the triphenylphosphine-induced insertion of carbon monoxide in acetonitrile proceeds with retention of configuration.
