4277-29-6

Basic information

• Product Name: CYCLOHEPTANECARBALDEHYDE
• Synonyms: CYCLOHEPTANECARBALDEHYDE;CYCLOHEPTANECARBOXALDEHYDE;RARECHEM AK ML 0066;formylcycloheptane
• CAS NO: 4277-29-6
• Molecular Formula: C8H14O
• Molecular Weight: 126.2
• EINECS: 224-279-5
• Mol File: 4277-29-6.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 184 °C at 760 mmHg
• Flash Point: 58.7 °C
• Appearance: /
• Density: 0.965g/cm³
• Vapor Pressure: 0.748mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: CYCLOHEPTANECARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOHEPTANECARBALDEHYDE(4277-29-6)
• EPA Substance Registry System: CYCLOHEPTANECARBALDEHYDE(4277-29-6)

Safety Data

• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39
• RIDADR: 1989
• Hazardous Substances Data: 4277-29-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 87, p. 1353, 1965 DOI: 10.1021/ja01084a034

InChI:InChI=1/C8H14O/c9-7-8-5-3-1-2-4-6-8/h7-8H,1-6H2

Upstream product

• 6975-19-5 1-oxa-spiro[2.6]nonane-2-carboxylic acid ethyl ester 
• 931-88-4 cis-Cyclooctene 
• 2453-46-5 cycloheptyl chloride 
• 122-51-0 orthoformic acid triethyl ester 
• 104563-23-7 Sodium; 1-oxa-spiro[2.6]nonane-2-carboxylate 
• 113388-84-4 Formic acid cycloheptylidenemethyl ester 
• 64-18-6 formic acid 
• 628-92-2 Cycloheptene 
• 95826-90-7 1,3,6-Cycloheptatrien-1-carbaldehyd 
• 2591-86-8 N-Formylpiperidine 
• 2404-35-5 cycloheptyl bromide 
• 4011-20-5 7,8-epoxy-1,3,5-cyclooctatriene 
• 36639-40-4 2,4,6-cycloheptatriene-1-carboxaldehyde dimethyl acetal 
• 1903-29-3 cycloheptylideneacetic acid 

Downstream Products

• 1460-16-8 cycloheptanoic acid 
• 75024-32-7 cycloheptyl formate 
• 512177-27-4 4-acetyl-5-cycloheptyl-3-hydroxy-1-(4-methylphenyl)-1,5-dihydro-2H-pyrrol-2-one 
• 3349-73-3 cycloheptanone 2,4-dinitrophenylhydrazone 
• 4448-75-3 cycloheptylmethanol 
• 1098107-83-5 C₁₆H₂₁Cl₃O₃S 

Relevant articles and documents

An Organocatalytic Access to Spiro[45]decanes and Spiro[4.6]undecanes Containing Aminolactones and 3-Aminopyrrolidines

The organocatalyzed Mannich coupling of cyclic carboxaldehydes allowed the concise and simple preparation of spirocyclic aminolactones. Their conversion into pharmaceutically relevant spiro[4.5]cyclic and spiro[4.6]cyclic 3-aminopyrrolidines is also described.

BIARYL PYRAZOLES AS NRF2 REGULATORS

The present invention relates to biaryl pyrazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.

An Effective Pd-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid

An effective palladium-catalyzed regioselective hydroformylation of olefins with formic acid is described. The ligand plays a crucial role in directing the reaction pathway. Linear aldehydes can be obtained in up to 93% yield with >20:1 regioselectivity using 1,3-bis(diphenylphosphino)propane (dppp) as the ligand. The reaction process is operationally simple and requires no syngas.