4278-95-9

Usage

General Description

2,4,6-trimethyl-4-(prop-2-en-1-yl)cyclohexa-2,5-dien-1-one, also known as pulegone, is a chemical compound commonly found in the essential oils of certain plants, including peppermint and pennyroyal. It is a colorless liquid with a pleasant odor and is frequently used in the production of menthol flavorings and perfumes. Pulegone has been found to have insecticidal properties and is used as a natural insect repellent. However, it is also known to have toxic effects when consumed in large quantities and has been regulated by some countries due to its potential to cause liver damage.

Upstream product

• 527-60-6 Mesitol 
• 106-95-6 allyl bromide 
• 762-72-1 allyl-trimethyl-silane 
• 41389-02-0 4-benzyl-2,4,6-trimethylcyclohexa-2,5-dien-1-one 
• 5450-46-4 1,3,5-trimethyl-2-[(prop-2'-en-1'-yl)oxy]benzene 

Downstream Products

• 67471-87-8 3-(1,3,5-Trimethyl-4-oxo-cyclohexa-2,5-dienyl)-propionic acid 
• 37829-32-6 4-Allyl-1,2,4,6-tetramethyl-cyclohexa-2,5-dienol 
• 37723-15-2 1-Allyl-2,3,4,6-tetramethylbenzol 
• 37723-14-1 2-(but-3-en-1-yl)-1,3,5-trimethylbenzene 
• 41389-67-7 3-Allyl-mesitol 
• 4810-05-3 2,4,6-trimethylallylbenzene 
• 67471-86-7 4-(3-hydroxypropyl)-2,4,6-trimethyl-2,5-cyclohexadien-1-one 

Relevant academic research and scientific papers

On the way to an oxidative Hosomi-Sakurai reaction

An oxidative allylation process mediated by a hypervalent iodine reagent has been performed on polysubstituted phenols. This reaction, occurring in useful to good yields, leads to a rapid access to dienones containing a quaternary carbon center. Georg Thieme Verlag Stuttgart.

Electron transfer induced dissociations of 2- and 4-alkyl cyclohexadienones

Several 2- and 4-alkylcyclohexadienones were prepared and shown to accept electrons to produce ketyl radical anions that dissociated rapidly at room temperature to release carbon-centered radicals and an aromatic phenoxide type anion. In the PET process with benzyl-substituted cyclohexadienones, initiated with triethylamine, the benzyl radicals dimerised or abstracted an H-atom from solvent. In electrochemical reductions, and in reductions with alkali metals in liquid ammonia, the benzyl radicals were further reduced to anions.

Organoaluminum-Promoted Rearrangement of Allyl Phenyl Ethers

The Claisen rearrangement of allyl phenyl ethers with exceptionally bulky, oxygenophilic methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide) (reagent A) is found to exhibit an unusual behavior not observable in the ordinary thermal and Lewis acid-induc