427886-41-7

Basic information

• Product Name: 3-Pyridinecarboxylic acid, 6-(3,4,5-trimethoxyphenyl)-, ethyl ester
• CAS NO: 427886-41-7
• Molecular Formula: C17H19NO5
• Molecular Weight: 317.342
• Mol File: 427886-41-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxylic acid, 6-(3,4,5-trimethoxyphenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 6-(3,4,5-trimethoxyphenyl)-, ethyl ester(427886-41-7)
• EPA Substance Registry System: 3-Pyridinecarboxylic acid, 6-(3,4,5-trimethoxyphenyl)-, ethyl ester(427886-41-7)

Safety Data

• Hazardous Substances Data: 427886-41-7(Hazardous Substances Data)

Upstream product

• 49608-01-7 6-chloro-3-pyridinecarboxylic acid ethyl ester 
• 182163-96-8 3,4,5-trimethoxyphenylboronic Acid 

Downstream Products

• 427886-42-8 5-hydroxymethyl-2-(3,4,5-trimethoxyphenyl)-pyridine 

Relevant articles and documents

ERYTHROPOIETIN PRODUCTION ACCELERATOR

The present invention relates to a preventive or therapeutic agent for pathological conditions caused by reduced production of erythropoietin, or for anemia, or for chronic anemia, renal anemia, aplastic anemia, or pure red cell aplasia, the agent comprising, as an active ingredient, a cyclic amine compound represented by the following formula (1): wherein, ???R1, R2 and R3 each independently represent a hydrogen atom, a halogen atom, or hydroxy, alkyl, halogen-substituted alkyl, alkoxy, alkylthio, carboxyl, alkoxycarbonyl or alkanoyl group; ???W1 and W2 each independently represent N or CH; ???X represents O, NR4, CONR4 or NR4CO; ???R4 each represents a hydrogen atom, or an alkyl, alkenyl, alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted aralkyl, or substituted or unsubstituted heteroaralkyl group; and ???l, m and n each represents a number of 0 or 1, or a salt thereof or a solvate thereof.

Cyclic amine compounds and pharmaceutical composition containing the same

A cyclic amine compound represented by the following general formula (1): wherein, R1, R2 and R3 each independently represent a hydrogen atom or an alkoxy group; W1 and W2 each independently represent N or CH; X represents O, NR4, CONR4 or NR4CO; R4 represents a hydrogen atom, or an alkyl, aryl, heteroaryl, aralkyl, or heteroaralkyl group; and l, m and n each represents a number of 0 or 1, a salt thereof and a hydrate thereof are provided. These compounds have inhibitory effects on both cell adhesion and cell infiltration and are useful as anti-asthmatic agents, anti-allergic agents, anti-rheumatic agents, anti-arteriosclerotic agents, anti-inflammatory agents, anti-Sjogren's syndrome agents or the like.

Unsymmetrical cyclic diamine compound

A cyclic diamine compound of formula (1): wherein A is (CH2)n, (CH2)n—CH═CH, CO—(CH2)n or CO—(CH2)n—CH═CH, in which n is a number of 0 to 3; Z represents a formula (2) or (3): in which R1, R2, R4, R5 and R6 are individually a hydrogen atom, alkyl group, alkoxy group, halogen atom or nitro group; R3 is a hydrogen atom, alkyl group, alkoxy group, halogen atom, nitro group, naphthyl group, or phenyl group which may be substituted by 1 to 3 substituents selected from the group consisting of alkyl groups, alkoxy groups, halogen atoms, a nitro group and a phenyl group; and X and Y are individually CH or a nitrogen atom; and m is 1 or 2; an acid-addition salt thereof, or a hydrate thereof, and a medicine containing such a compound.