4279-85-0Relevant academic research and scientific papers
Cyclic peptide antifungal agents
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, (2008/06/13)
Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I STR1 where: R', R", R'", Rx1, Rx2, Ry1, Ry2, Ry3, Ry4, and R0 are as defined hereinabove; and R2 is STR2 R3 is STR3 R3a is C1 -C6 alkyl or C1 -C6 alkoxy; R3b and R3c are independently phenyl or naphthyl; R3d is C1 -C12 alkyl, C1 -C12 alkoxy or --O --(CH2)m -[O--(CH2)n ]p --O--(C1 -C12 alkyl); m is 2, 3 or 4; n is 2, 3 or 4; p is 0 or 1; or a pharmaceutically acceptable salt thereof.
