42790-44-3 Usage
Chemical structure
Piperidine derivative with a benzyl group at the first position and a vinyl group at the fourth position.
Applications
a. Building block in the synthesis of pharmaceuticals and agrochemicals.
b. Potential use in the treatment of cancer and Alzheimer's disease.
c. Investigated for psychoactive effects and potential applications in neuroscience.
Functional groups
a. Benzyl group (C6H5-CH2-)
b. Vinyl group (C=CH2)
c. Piperidine ring (C5H9N)
Chemical properties
a. Reactivity with various reagents due to the presence of the vinyl group.
b. Potential for substitution reactions at the benzyl and piperidine moieties.
Appearance
Likely a solid or oily liquid, depending on the conditions.
Solubility
Soluble in organic solvents such as ethanol, methanol, and dichloromethane.
Stability
a. Stable under normal conditions, but may react with strong acids, bases, or oxidizing agents.
b. Should be stored in a cool, dry place and protected from light.
Potential hazards
May be harmful if swallowed, inhaled, or absorbed through the skin.
Precautions
Use appropriate personal protective equipment (PPE) and follow proper handling procedures.
Synthesis
a. Can be synthesized through various methods, such as the reaction of a piperidine derivative with a benzyl halide and subsequent vinylation.
b. Optimization of reaction conditions may be necessary to obtain the desired product with high yield and purity.
Check Digit Verification of cas no
The CAS Registry Mumber 42790-44-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,9 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 42790-44:
(7*4)+(6*2)+(5*7)+(4*9)+(3*0)+(2*4)+(1*4)=123
123 % 10 = 3
So 42790-44-3 is a valid CAS Registry Number.
42790-44-3Relevant academic research and scientific papers
Chlorotrifluoromethylation of Terminal Olefins by Atom Transfer-Type Radical Reaction Catalyzed by Cobalt Complexes
Maeda, Kazuki,Kurahashi, Takuya,Matsubara, Seijiro
supporting information, p. 4613 - 4616 (2019/07/18)
A cobalt porphyrin-catalyzed chlorotrifluoromethylation reaction of olefins is described. The use of CF3SO2Cl as the CF3 radical source and a cobalt catalyst enabled the selective addition of CF3 radicals under thermal conditions. Various functional groups such as esters and Ar–X moieties, which can be reactive with low valent transition metal catalysts, were well-tolerated in this catalytic process. A highly functionalized alkaloid derivative was also tolerated as a substrate. As a demonstration of the bio-inspired catalytic system, catalytic usage of vitamin B12, which is the commercially available form of the natural cobalt porphyrinoid, was employed, and diastereoselective chlorotrifluoromethylation of the alkaloid molecule was achieved.
Fused pyridine derivatives
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Example 318, (2010/01/30)
The present provides a condensed pyridine compound (I) represented by the following formula: (wherein, R2represents ring A represents benzene ring, pyridine ring, thiophene ring or furan ring; and B represents its pharmaceutically acceptable salt or hydrates thereof, which is a clinically useful medicament having a serotonin antagonism, in particular, that for treating, ameliorating or preventing spastic paralysis or central muscle relaxants for ameliorating myotonia.
