427923-03-3Relevant academic research and scientific papers
Mannich-type reaction of N,O-acetals with ketones mediated by a combination of TiCl4 and PhSiCl3
Kamogawa, Satoshi,Ikeda, Takashi,Kuriyama, Masami,Matsumura, Yoshihiro,Onomura, Osamu
, p. 325 - 332 (2010)
A combination of TiCl4 and PhSiCl3 efficiently conducts the Mannich-type reaction of N,O-acetals with ketones to afford α-substituted cyclic amine derivatives in good yields. This method was applicable to preparation of azabicyclo co
