42811-85-8

Basic information

• Product Name: (E)-1,3-bis(furan-2-yl)-2-propen-1-one
• Synonyms: (E)-1,3-bis(furan-2-yl)-2-propen-1-one
• CAS NO: 42811-85-8
• Molecular Weight: 188.183
• Mol File: 42811-85-8.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (E)-1,3-bis(furan-2-yl)-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,3-bis(furan-2-yl)-2-propen-1-one(42811-85-8)
• EPA Substance Registry System: (E)-1,3-bis(furan-2-yl)-2-propen-1-one(42811-85-8)

Safety Data

• Hazardous Substances Data: 42811-85-8(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 1192-62-7 1-(2-furyl)-1-ethanone 

Downstream Products

• 16753-13-2 3,5-di(furan-2-yl)-1-phenyl-4,5-dihydro-1H-pyrazole 
• 52395-51-4 4-(1,3-di-furan-2-yl-3-oxo-propyl)-1,2-diphenyl-pyrazolidine-3,5-dione 
• 936011-81-3 3,5-di(furan-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide 
• 3878-19-1 fuberidazole 
• 1024195-36-5 ethyl 4,6-bis(furan-2-yl)-2-oxocyclohex-3-ene-1-carboxylate 
• 1269059-64-4 (2R,3S)-tert-butyl 2-(diphenylmethyleneamino)-3,5-di(furan-2-yl)-5-oxopentanoate 
• 98677-49-7 3,5-di-furan-2-yl-4,5-dihydro-pyrazole-1-carbothioic acid anilide 
• 791828-03-0 1-(N-allylthiocarbamoyl)-3,5-di(2-furyl)-2-pyrazoline 
• 1028209-04-2 ethyl 3-amino-4,6-di-(2-furyl)thieno[2,3-b]pyridine-2-carboxylate 
• 1028209-00-8 4,6-di(furan-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile 

Relevant articles and documents

Synthesis and studies on antidepressant and anticonvulsant activities of some 3-(2-furyl)-pyrazoline derivatives

Twelve 1-phenyl-, 1-thiocarbamoyl- and 1-N-substituted thiocarbamoyl-3-(2-furyl)-5-phenyl/(2-furyl)-2-pyrazoline derivatives were synthesized. The chemical structures of the compounds were proved by IR, 1H NMR, Mass spectrometric data and micro

Ultrasound-assisted rapid and efficient one-pot synthesis of furanyl spirooxindolo and spiroquinoxalinopyrrolizidines by 1,3-dipolar cycloaddition: a green protocol

Efficient synthesis of novel spirooxindolo and spiroquinoxalinopyrrolizidine derivatives was expediently accomplished with regioselectivity via one-pot, three-component 1,3-dipolar cycloaddition using ultrasonication. Chalcones derived from both heteroaryl methyl ketones and furfural were used as dipolarophiles in these reactions. The synthesized compounds were analyzed by 1H and 13C nuclear magnetic resonance (NMR), mass spectrometry, and elemental (CHN) analysis. Single-crystal X-ray diffraction studies of one of the compounds (11d) proved the structure and regiochemistry of the cycloaddition. The ultrasound methodology is clearly advantageous, and the desired products were obtained in moderate to good yield in shorter reaction time compared with conventional heating and fusion methods.

Triethylamin-mediated addition of 2-aminoethanethiol hydrochloride to chalcones: Synthesis of 3-(2-aminoethylthio)-1-(aryl)-3-(thiophen-2-yl) propan-1-ones and 5,7-diaryl-2,3,6, 7-tetrahydro-1,4-thiazepines

The triethylamin-mediated addition of 2-aminoethanethiol hydrochloride to chalcone analogs was investigated. This addition, bearing a 2-thienyl group at the 3-position, gave the only addition adduct at room temperature in 3 h, whereas the chalcones bearing the 2-furyl group at the 1-position gave an addition-cyclization product (1, 4-thiazepine) in the same conditions. The effect of the groups to the reaction was investigated by changing the 1- and 3-position groups. The chalcones bearing the 2-thienyl group at the 1-position and the others afforded the mixture of products in different ratio at rt for 0.5-24 h. Moreover, the addition-cyclization products (1,4-thiazepine) were obtained under reflux conditions in 36 h. The structures of the synthesized compounds were elucidated by 1H NMR, 13C NMR, infrared, and elemental analysis.