42829-08-3

Basic information

• Product Name: 5(4-chlorophenyl)-2-pentanone
• Synonyms: 5(4-chlorophenyl)-2-pentanone;5-(4-Chlorophenyl)pentan-2-one
• CAS NO: 42829-08-3
• Molecular Weight: 196.677
• Mol File: 42829-08-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5(4-chlorophenyl)-2-pentanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4-chlorophenyl)-2-pentanone(42829-08-3)
• EPA Substance Registry System: 5(4-chlorophenyl)-2-pentanone(42829-08-3)

Safety Data

• Hazardous Substances Data: 42829-08-3(Hazardous Substances Data)

Usage

Classification

Synthetic designer drug, belonging to the class of cathinones

Effects

Stimulating and psychoactive effects on the central nervous system, similar to amphetamines and cocaine

Recreational use

Known for its euphoric and stimulating effects

Legal status

Illegal in many countries, posing serious health risks.

Upstream product

• 106-39-8 bromochlorobenzene 
• 111957-98-3 Pent-4-en-2-ol 
• 6529-53-9 1-(2-bromoethyl)-4-chlorobenzene 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 2344-71-0 5-phenylpentan-2-ol 
• 103094-38-8 1-hydroxy-1-methyl-1,2,3,4,6,9-hexahydronaphthalene 

Relevant articles and documents

Electroreductive Intramolecular Coupling of Nonconjugated Aromatic Ketones

The electroreduction of nonconjugated aromatic ketones gave intramolecularly coupled products.The best result was obtained using an Sn cathode in i-PrOH containing tetraalkylammonium salt as a supporting electrolyte.This reductive cyclization proceeded with remarkable stereoselectivity, and the cis isomer was obtained exclusively.A variety of new bi- and polycyclic compounds were synthesized.The reaction mechanism was studied, and it was suggested that the anion radical generated by one-electron transfer to a carbonyl group attacks an aromatic ring intramolecularly.The choice of counter cation of the anion radical was critical for the reductive cyclization.Other reductive methods employing metal reducing agents were also studied.Reduction with Na in HMPA-THF gave the same cyclized product, though the yield was lower than that with the electroreduction.