4283-48-1

Basic information

• Product Name: 2α,12β-Dihydroxypicrasane-1,11,16-trione
• Synonyms: 2α,12β-Dihydroxypicrasane-1,11,16-trione;Shinjulactone H
• CAS NO: 4283-48-1
• Molecular Formula: C20H28O6
• Molecular Weight: 364.43272
• Mol File: 4283-48-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2α,12β-Dihydroxypicrasane-1,11,16-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 2α,12β-Dihydroxypicrasane-1,11,16-trione(4283-48-1)
• EPA Substance Registry System: 2α,12β-Dihydroxypicrasane-1,11,16-trione(4283-48-1)

Safety Data

• Hazardous Substances Data: 4283-48-1(Hazardous Substances Data)

Upstream product

• 139276-56-5 2,12-Dimethoxy-2,12-picradiene-1,11,16-trione 16-(ethylene ketal) 
• 139276-57-6 2,12-Dimethoxy-1β-hydroxy-2,12-picradiene-11,16-dione 16-ethylene acetal 
• 139276-58-7 Isopicrasin B 
• 112667-46-6 shinjuglycoside F 
• 139346-55-7 1β-Hydroxy-12β-methoxypicrasane-2,11,16-trione 

Relevant articles and documents

A Partial Synthesis of (-)-Shinjulactone H from (+)-Quassin

A partial synthesis of (-)-shinjulactone H (3) from (+)-quassin (1) required the selective manipulation of two similar O-methyldiosphenol groups.Protection of the δ-lactone in 1 as an ortho ester, selective reduction of the C-1 carbonyl group, hydrolysis of the resulting enol ether in the A ring, and catalytic hydrogenation of the O-methyldiosphenol in the C ring delivered an intermediate possessing an α-ketol group in the A ring and an α-methoxy ketone group in the C ring.Demethylation and concomitant α-ketol tautomerization in the A ring delivered (-)-shinjulactone H (3).