42835-54-1

Usage

Molecular Structure

1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid has a complex molecular structure that belongs to the class of quinoline carboxylic acids.

Medicinal Chemistry

It is commonly used in medicinal chemistry and has potential biological and pharmaceutical applications.

Building Block

It is often used as a building block in the synthesis of various pharmaceutical drugs and molecular probes.

Antimicrobial and Antiparasitic Activity

It may also have potential antimicrobial and antiparasitic activity, making it an important compound in drug discovery and development.

Upstream product

• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 6687-87-2 (3,4-dihydro-2H-quinolin-1-ylmethylene)-malonic acid diethyl ester 

Downstream Products

• 73253-21-1 (6R)-3-acetoxymethyl-8-oxo-7t-[(R)-2-(1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carbonylamino)-2-phenyl-acetylamino]-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 

Relevant academic research and scientific papers

NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS

The present invention relates to 14- or 15-membered macrolides substituted at the 4" position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infections in a human or animal body.

β-Lactam series compound and antibacterial pharmaceutical composition containing the same

A β-lactam series compound represented by the formula (I): STR1 wherein R1 represents a hydrogen atom or a lower alkyl group; R2 represents a hydrogen atom; R3 represents a halogen atom, a nitro group, an amino group, a hydroxy group, a lower alkyl group, a lower alkoxy group, a lower alkanoylamino group, a lower alkanesulfonyloxy group or a group represented by the formula STR2 where R5 represents a hydrogen atom, a lower alkanoyl group, or a lower alkanesulfonyl group; R4 represents a hydrogen atom or a hydroxy group; n is 0 or 1; l is 0, 1 or 2; and A represents --C(CH3)2 --CH(COOH)-- or --CH2 C(CH2 R6)=C(COOH)-- where R6 represents a lower alkanoyloxy group, a group represented by the formula STR3 where R7 and R8 each represents a lower alkyl group and when n is 0, R1 and R2 can combine to form a cyclohexane ring together with the carbon atoms to which they are attached, and pharmaceutically acceptable salts thereof as well as a method for preparing same are disclosed. These compounds have antimicrobial activity.