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2-(4-Chloro-benzenesulfonyl)-4-methyl-phenylamine is an organic compound with the molecular formula C13H12ClNO2S. It is a derivative of phenylamine, featuring a 4-methyl group and a 4-chloro-benzenesulfonyl group attached to the phenyl ring. 2-(4-Chloro-benzenesulfonyl)-4-methyl-phenylamine is characterized by its white crystalline appearance and is soluble in organic solvents. It is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of certain sulfonamide drugs. Due to its reactivity and potential applications, it is important to handle this chemical with care, adhering to proper safety protocols.

4284-60-0

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4284-60-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4284-60-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,8 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4284-60:
(6*4)+(5*2)+(4*8)+(3*4)+(2*6)+(1*0)=90
90 % 10 = 0
So 4284-60-0 is a valid CAS Registry Number.

4284-60-0Relevant academic research and scientific papers

Intramolecular aromatic 1,5-hydrogen transfer in free radical reactions III. Reactivity of diaryl ketones, ethers, thioethers, sulfoxydes, and sulfones. An experimental and theoretical study

Karady, Sandor,Cummins, Jordan M.,Dannenberg,Del Rio, Emma,Dormer, Peter G.,Marcune, Benjamin F.,Reamer, Robert A.,Sordo, Tomas L.

, p. 1175 - 1178 (2003)

(Matrix presented) Experiments show that free radical hydrogen shift is significant in the Pschorr cyclization of diphenyl ethers (X = O) and thioethers (X = S) and does not take place with sufoxides (X = SO) and sulfones (X = SO2). DFT calculations of the product ratios, activation energies, rate constants for H-transfers, and ring-closings at the UB3PW91/6-31G(d,p) level are in excellent agreement with the experimental results reported here and elsewhere in the literature.

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