428454-82-4Relevant academic research and scientific papers
The asymmetric Michael-type alkylation of chiral β-enamino esters: Critical role of a benzyl ester group in the racemization of adducts
Pizzonero, Mathieu,Hendra, Frederic,Delarue-Cochin, Sandrine,Tran Huu-Dau, Marie-Elise,Dumas, Francoise,Cave, Christian,Nour, Mohammed,D'Angelo, Jean
, p. 3853 - 3857 (2005)
In contrast with keto diester (R)-10a bearing a methyl ester group at the quaternary carbon center, the benzyl ester analogue (R)-10a partially racemized during workup, thereby revealing that the nature of the ester group at the quaternary carbon center h
Asymmetric synthesis of glutamate derivatives
Seck, Rokhayatou,Gassama, Abdoulaye,Nour, Mohammed,Demange, Luc,Cavé, Christian
, p. 51 - 62 (2017/06/19)
Analogs of glutamic acid were synthesized through the asymmetric Michael reaction using chiral acyclic β-enaminoesters and various Michael acceptors. The influence of the alkoxy group of the enaminoesters and also the nature of the olefins in the presence
Michael reaction of acyclic β-enaminoesters derived from α-alkyl-β-ketoesters and chiral α-methylbenzylamine: Stereoselective generation of quaternary carbon centres
Maiti,Ghoshal,Mukhopadhyay,Achari,Banerjee
, p. 1072 - 1080 (2007/10/03)
Michael reaction of electrophilic olefins with acyclic β-enaminoester substrates derived from α-substituted β-ketoesters and (R)- or (S)-α-methylbenzylamine under neutral conditions resulted in the enantioselective formation of quaternary centres. The add
