428514-91-4 Usage
Uses
Used in Organometallic Chemistry:
(R)-2-[(Diphenylphosphino)methyl]pyrrolidine, min. 97% is used as a ligand in organometallic chemistry for its ability to form stable complexes with metal catalysts. This enhances the efficiency and selectivity of various metal-catalyzed reactions.
Used in Asymmetric Synthesis:
In the field of asymmetric synthesis, (R)-2-[(Diphenylphosphino)methyl]pyrrolidine, min. 97% is used as a chiral ligand to induce enantioselectivity in chemical reactions. This allows for the production of enantiomerically pure compounds, which are essential in the synthesis of pharmaceuticals and agrochemicals.
Used in Pharmaceutical Industry:
(R)-2-[(Diphenylphosphino)methyl]pyrrolidine, min. 97% is used as a building block or intermediate in the synthesis of enantiomerically pure drugs and bioactive compounds. Its chiral nature makes it a valuable component in the development of new medications with improved efficacy and reduced side effects.
Used in Research Applications:
Due to its high purity and unique structural features, (R)-2-[(Diphenylphosphino)methyl]pyrrolidine, min. 97% is used in research applications to explore its potential in various chemical reactions and to understand its properties and reactivity. This helps in advancing the knowledge of organometallic chemistry and asymmetric synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 428514-91-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,8,5,1 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 428514-91:
(8*4)+(7*2)+(6*8)+(5*5)+(4*1)+(3*4)+(2*9)+(1*1)=154
154 % 10 = 4
So 428514-91-4 is a valid CAS Registry Number.
428514-91-4Relevant academic research and scientific papers
Auto-Tandem Cooperative Catalysis Using Phosphine/Palladium: Reaction of Morita–Baylis–Hillman Carbonates and Allylic Alcohols
Chen, Peng,Chen, Zhi-Chao,Li, Yue,Ouyang, Qin,Du, Wei,Chen, Ying-Chun
, p. 4036 - 4040 (2019/02/24)
Auto-tandem catalysis (ATC), in which a single catalyst promotes two or more mechanistically different reactions in a cascade pattern, provides a powerful strategy to prepare complex products from simple starting materials. Reported here is an unprecedented auto-tandem cooperative catalysis (ATCC) for Morita–Baylis–Hillman carbonates from isatins and allylic carbonates using a simple Pd(PPh3)4 precursor. Dissociated phosphine generates phosphorus ylides and the Pd leads to π-allylpalladium complexes, and they undergo a γ-regioselective allylic–allylic alkylation reaction. Importantly, a cascade intramolecular Heck-type coupling proceeds to finally furnish spirooxindoles incorporating a 4-methylene-2-cyclopentene motif. Experimental results indicate that both Pd and phosphine play crucial roles in the catalytic Heck reaction. In addition, the asymmetric versions with either a chiral phosphine or chiral auxiliary are explored, and moderate results are obtained.
METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS
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Page/Page column 41, (2009/01/24)
The present application is directed to i) a two-step method for synthesizing phosphme-ammophosphme (P,N,P) ligands, ii) the use of such ligands in the preparation of metal complexes as hydrogenation catalysts, and iii) ammophosphme (P,N) and phosphme-ammo
