42856-29-1

Usage

Uses

Used in Pharmaceutical Industry:
(2S)-2-methylbicyclo[2.2.1]heptane-2-carboxylic acid is used as a potential building block for the development of pharmaceutical compounds due to its unique bicyclic structure and functional groups. Its ability to engage in specific molecular interactions could contribute to the creation of new drugs with targeted therapeutic effects.
Used in Chemical Industry:
In the chemical industry, (2S)-2-methylbicyclo[2.2.1]heptane-2-carboxylic acid may serve as an intermediate in the synthesis of various chemical products. Its carboxylic acid group can participate in a range of chemical reactions, making it a versatile component in the production of specialty chemicals, materials, or other organic compounds.

Upstream product

• 92007-58-4 (1S)-endo-2-methylbicyclo<2.2.1>hept-5-ene-2-carboxylic acid 
• 176774-74-6 (1S-endo)-2-methylbicyclo<2.2.1>hept-5-ene-2-carboxylic acid 
• 20705-19-5 dichlorotrifluoroethane sulphenic acid chloride 
• 120-74-1 endo-norbornenecarboxylic acid 
• 32190-82-2 (+/-)-2-methyl-norborn-5-ene-2exo-carboxylic acid 

Downstream Products

• 80605-63-6 endo-2-Methyl-exo-2-norbornylaminhydrochlorid 
• 21956-67-2 2-endo-Methyl-norbornan-carbonsaeure-(2exo)-chlorid 
• 80605-51-2 endo-2-Methyl-exo-2-norbornylmethylketonoximpikrat 

Relevant academic research and scientific papers

Asymmetric syntheses with a new optically active perhydronaphthalene based chiral auxiliary

(1R,4aS,8S,8aS)-8-(5'-Methoxy-2'-methylphenyl)-8-methyldecahydro-1-nap hthalenol 3a is a highly efficient chiral auxiliary in the Diels-Alder addition of its acrylate ester 5 and in the DIBAL-H and Grignard reactions of its phenylglyoxylate ester 7.

Synthesis and Photochemistry of Heterocyclic Norbornenyl Ketones

A series of endo-5-norbonenyl ketones 1 was prepared which contained the following heterocyclic rings: 2-furyl, 2-thienyl, N-methyl-2-pyrryl, 3,5-dimethyl-4-isoxazolyl, 5-methyl-3-isoxazolyl and 2,5-dimethyl-4-oxazolyl groups.Oxetanes 2 were produced from the ketones either by direct irradiation (λ > 300 nm) or by use of photosensitizers.The two isoxazolyl systems were irradiated at 254 nm and found to lead to additional products, two of which were identified as 2H-azirines 16.It is probable that the latter were formed from an upper level excited state.

HIGHLY DIASTEREOSELECTIVE DIELS-ALDER REACTION OF OPTICALLY ACTIVE ETHYL 2-p-TOLYLSULFINYLMETHYLENEPROPIONATE WITH CYCLOPENTADIENE

Stereochemistry of the Diels-Alder reaction of ethyl Z- and E-2-p-tolylsulfinylmethylenepropionate with cyclopentadiene has been studied.The high diastereoselectivity was observed especially in the case of exo-cycloaddition.