428840-30-6Relevant academic research and scientific papers
CuBr2 mediated synthesis of 2-Aminothiazoles from dithiocarbamic acid salts and ketones
Zhang, Baohua,Shi, Lanxiang
, p. 1134 - 1139 (2019)
In a one-pot procedure, CuBr2 has been used as a efficient desulfurizing agent in the synthesis of 2-aminothiazoles by the condensation of in situ-generated 1-substituted thioureas from their dithiocarbamic acid salts, with in situ-generated α-bromoketones from ketones. All reactions were carried out under optimized reaction conditions and gave the target products in 61–95% yield.
