42916-68-7

Basic information

• Product Name: 1-Pentanone, 1-(3-fluorophenyl)-
• CAS NO: 42916-68-7
• Molecular Formula: C11H13FO
• Molecular Weight: 180.222
• Mol File: 42916-68-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Pentanone, 1-(3-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanone, 1-(3-fluorophenyl)-(42916-68-7)
• EPA Substance Registry System: 1-Pentanone, 1-(3-fluorophenyl)-(42916-68-7)

Safety Data

• Hazardous Substances Data: 42916-68-7(Hazardous Substances Data)

Usage

Compound class

Ketone

Physical state

Colorless liquid

Odor

Sweet, floral

Uses

Flavor and fragrance agent in food and cosmetics, intermediate in pharmaceutical synthesis, production of pesticides, potential use in polymer and other industrial chemical processes

Safety precautions

May be harmful if ingested or inhaled, can cause skin and eye irritation, handle with caution.

Upstream product

• 680-31-9 N,N,N,N,N,N-hexamethylphosphoric triamide 
• 109-72-8 n-butyllithium 
• 403-54-3 m-Fluorobenzonitrile 
• 1598-19-2 1-(3-fluorophenyl)-pentan-1-ol 
• 226260-01-1 3-fluoro-N-methoxy-N-methylbenzamide 
• 684648-38-2 2-(3-fluoro-phenyl)-[1,3,2]dioxaborinane 
• 120-92-3 cyclopentanone 

Relevant articles and documents

Suzuki-Miyaura coupling of simple ketones via activation of unstrained carbon-carbon bonds

Here, we describe that simple ketones can be efficiently employed as electrophiles in Suzuki-Miyaura coupling reactions via catalytic activation of unstrained C-C bonds. A range of common ketones, such as cyclopentanones, acetophenones, acetone and 1-indanones, could be directly coupled with various arylboronates in high site-selectivity, which offers a distinct entry to more functionalized aromatic ketones. Preliminary mechanistic study suggests that the ketone α-C-C bond was cleaved via oxidative addition.

Axially chiral NHC-Pd(II) complexes in the oxidative kinetic resolution of secondary alcohols using molecular oxygen as a terminal oxidant

(Chemical Equation Presented) Axially chiral N-heterocyclic carbene (NHC) Pd(II) complexes were prepared from optically active 1,1′-binaphthalenyl- 2,2′-diamine (BINAM) and H8-BINAM and applied in the oxidative kinetic resolution of secondary alcohols using molecular oxygen as a terminal oxidant. The corresponding sec-alcohols can be obtained in good yields with moderate to good enantioselectivities.

Mechanistic evaluation of dissociative electron-transfer and nucleophilic substitution reactions

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