42924-30-1

Upstream product

• 621-23-8 1,2,3-trimethoxybenzene 
• 107-13-1 acrylonitrile 
• 830-79-5 2,4,6-trimethoxybenzaldehyde 
• 106800-18-4 3-hydroxy-3-(2,4,6-trimethoxyphenyl)propanenitrile 

Downstream Products

• 106800-19-5 1-(2,4,6-trimethoxyphenyl)-4,4-dimethylhex-5-en-3-one 
• 106800-20-8 1-(2,4,6-trimethoxyphenyl)-3-allyl-4,4-dimethylhex-5-en-3-ol 
• 106800-21-9 2,2-dimethyl-exo-3-(2-(2,4,6-trimethoxyphenyl)ethyl)bicyclo<3.2.0>heptan-3-endo-ol 
• 106800-33-3 2,2-dimethyl-3-(2-(2-hydroxy-4,6-dimethoxyphenyl)ethyl)bicyclo<3.2.0>heptan-3-ol 

Relevant academic research and scientific papers

Addition of heterocycles to electron deficient olefins and alkynes catalyzed by gold(III)

A gold(III)-catalyzed hydroarylation of different olefins is reported here. AuCl3 works as an excellent catalyst to mediate reactions between various heterocycles and electron deficient olefins and alkynes under mild conditions. This gold(III)-based method tolerates different functional groups such as aldehyde, carboxylic acid, nitrile, and is highly efficient. We have shown that some of these reactions complete in minutes at room temperature.

Hydroxyl-Directed Regioselective Monodemethylation of Polymethoxyarenes

Methoxyl groups ortho to β-hydroxyethyl or γ-hydroxypropyl substituents in polymethoxybenzene derivatives were regioselectively demethylated with sodium thioethoxide in N,N-dimethylformamide.Methoxydihydrobenzofurans or methoxychromans were produced by cyclization of the monodemethylated β-hydroxyethyl or γ-hydroxypropyl derivatives, respectively.