42959-18-2

Basic information

• Product Name: 2-(2,2-dimethyl-1,3,6,2-dioxazasilocan-6-yl)ethanol
• CAS NO: 42959-18-2
• Molecular Formula: C₈H₁₉NO₃Si
• Molecular Weight: 205.3269
• Mol File: 42959-18-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 260.8°C at 760 mmHg
• Flash Point: 111.5°C
• Density: 1.05g/cm³
• Vapor Pressure: 0.00173mmHg at 25°C
• Refractive Index: 1.473
• CAS DataBase Reference: 2-(2,2-dimethyl-1,3,6,2-dioxazasilocan-6-yl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-dimethyl-1,3,6,2-dioxazasilocan-6-yl)ethanol(42959-18-2)
• EPA Substance Registry System: 2-(2,2-dimethyl-1,3,6,2-dioxazasilocan-6-yl)ethanol(42959-18-2)

Safety Data

• Hazardous Substances Data: 42959-18-2(Hazardous Substances Data)

Usage

Compound type

Silane-based compound

Usage

Different sources of media describe the Usage of 42959-18-2 differently. You can refer to the following data:
1. Protecting group for alcohols in organic synthesis
2. Synthesis of various pharmaceuticals and agrochemicals

Application

Reagent in modification of nucleosides, peptides, and proteins

Advantages

Stability and effectiveness in protecting hydroxyl groups

Field of use

Chemistry and biochemical research

Upstream product

• 102-71-6 triethanolamine 
• 1020-84-4 2,2,4,4,6,6,8,8-octamethyl-cyclotetrasilazane 
• 4669-59-4 bis(diethylamino)dimethylsilane 
• 78-62-6 diethoxy dimethylsilane 
• 1009-93-4 2,2,4,4,6,6-hexamethylcyclotrisilazane 

Downstream Products

• 58647-65-7 Diphenyl-acetic acid 2-(2,2-dimethyl-[1,3,6,2]dioxazasilocan-6-yl)-ethyl ester 
• 80510-93-6 Isonicotinic acid 2-(2,2-dimethyl-[1,3,6,2]dioxazasilocan-6-yl)-ethyl ester 
• 80510-95-8 (4-Chloro-phenoxy)-acetic acid 2-(2,2-dimethyl-[1,3,6,2]dioxazasilocan-6-yl)-ethyl ester 
• 57966-38-8 2-(4-Chloro-phenoxy)-2-methyl-propionic acid 2-(2,2-dimethyl-[1,3,6,2]dioxazasilocan-6-yl)-ethyl ester 
• 80510-91-4 Nicotinic acid 2-(2,2-dimethyl-[1,3,6,2]dioxazasilocan-6-yl)-ethyl ester 
• 2097-18-9 1-vinylsilatrane 

Relevant articles and documents

MEDIUM-SIZED SILICON-CONTAINING RINGS. IV. SILOCANE-SILATRANE TRANSFORMATIONS

We have discovered an intramolecular condensation of trimethylsilyl ethers of silocines with a phenyl substituent on the silicon atom that leads to the corresponding silatranes.For the preparation of N-(hydroxyethy) derivatives of silocines we have, for the first time, used the cyclosilylation of triethanolamine with a bis(dialkylamino)silane.It was found that in the exothermic reaction of trialkoxyalkylsilanes with N-(hydroxyethyl) derivatives of silocines and their trimethylsilyl ethers the yield of silatranes is only slighthly dependent on the nature of the substituent both in the silocines and in the alkoxysilanes.

Organosilicon esters derivated from triethanolamine. Synthesis and pharmacological properties

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