429665-92-9

Upstream product

• 20898-43-5 4-(2-tert-butoxycarbonylamino-2-methoxycarbonyl-ethyl)-1H-imidazole-1-carboxylic acid tert-butyl ester 
• 159707-15-0 3,5-dichlorobenzyl triflate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 60211-57-6 3,5-dichlorobenzyl alcohol 
• 4467-54-3 l-histidine methyl ester dihydrochloride 

Downstream Products

• 305335-31-3 (2S)-2-[[(2S)-3-[3-[(3,5-dichlorophenyl)methyl]imidazol-4-yl]-1-hydroxy-1-oxopropan-2-yl]amino]-4-methylpentanoic acid 
• 305335-31-3 2(R)-{1(S)-carboxy-2-[3-(3,5-dichloro-benzyl)-3H-imidazol-4-yl]-ethylamino}-4-methyl-pentanoic acid 
• 790201-42-2 (S)-2-amino-3-[3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl]Propionic Acid Methyl Ester 

Relevant academic research and scientific papers

Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors

Angiotensin-converting enzyme-related carboxypeptidase (ACE2) is a recently identified zinc metalloprotease with carboxypeptidase activity that was identified using our genomics platform. We implemented a rational design approach to identify potent and se