429686-59-9Relevant academic research and scientific papers
A torquoselective extrusion of isoxazoline N-oxides. Application to the synthesis of aryl vinyl and divinyl ketones for Nazarov cyclization
Canterbury, Daniel P.,Herrick, Ildiko R.,Um, Joann,Houk,Frontier, Alison J.
scheme or table, p. 3165 - 3179 (2009/09/05)
A mild, convenient reaction sequence for the synthesis of Nazarov cyclization substrates is described. The [3+2] dipolar cycloaddition of a nitrone and an electron-deficient alkyne gives an isolable isoxazoline intermediate, which upon oxidation undergoes stereoselective extrusion of nitrosomethane to give aryl vinyl or divinyl ketones.
Polarizing the nazarov cyclization: The impact of dienone substitution pattern on reactivity and selectivity
He, Wei,Herrick, Ildiko R.,Atesin, Tulay A.,Caruana, Patrick A.,Kellenberger, Colleen A.,Frontier, Alison J.
, p. 1003 - 1011 (2008/10/09)
The impact of dienone substitution on the Nazarov cyclization has been examined in detail. Substrates bearing different substituents at each of four positions on the dienone backbone were systematically probed in order to identify trends leading to higher
End-cap stabilized oligoynes: Model compounds for the linear sp carbon allotrope carbyne
Gibtner, Thomas,Hampel, Frank,Gisselbrecht, Jean-Paul,Hirsch, Andreas
, p. 408 - 432 (2007/10/03)
Three series of differently 3,5-disubstituted α,ω-diphenylpolyynes Ar-(C≡C)n-Ar (n=2, 4, 6, 8, 10) were synthesized under optimized Cadiot - Chodkiewicz conditions, isolated and completely characterized. These compounds can be considered as mod
