42989-99-1Relevant academic research and scientific papers
Efficient preparation of aminoxyacyl amides, aminoxy hybrid peptides, and α-aminoxy peptides
Katritzky, Alan R.,Avan, Ilker,Tala, Srinivasa R.
supporting information; experimental part, p. 8690 - 8694 (2010/01/16)
(Chemical Equation Presented) N-(Pg-α-aminoxy acids) 1a-g are converted to N-(Pg-α-aminoxyacyl)benzotriazoles 2a-g, which react under mild conditions with amines, α-amino acids/α-dipeptides, and α-aminoxy acids to give aminoxyacyl amides 3a-g, (3e+3e′), and (3g+3g′), aminoxy hybrid peptides 4a-h, (4a+4a′), 6a-d, 9a-e, (9a+9a′), and (9b+9b′), and α-aminoxy peptides 10a,b in good yields without racemization. 2009 American Chemical Society.
