43024-63-1 Usage
Uses
Used in Pharmaceutical Research:
Ethyl 3-bromo-7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylate is used as a key intermediate in the synthesis of novel drug candidates for various therapeutic applications. Its unique structural features allow for the exploration of its potential as a precursor to new pharmaceutical agents.
Used in Organic Synthesis:
In the field of organic synthesis, Ethyl 3-bromo-7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylate serves as a versatile reagent for the construction of complex organic molecules. Its presence of a bromine atom and hydroxyl group enables various synthetic transformations, making it a valuable building block for the development of advanced organic compounds.
Further studies are required to fully explore the potential of Ethyl 3-bromo-7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylate and its possible applications in different industries, including but not limited to pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 43024-63-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,2 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 43024-63:
(7*4)+(6*3)+(5*0)+(4*2)+(3*4)+(2*6)+(1*3)=81
81 % 10 = 1
So 43024-63-1 is a valid CAS Registry Number.
43024-63-1Relevant academic research and scientific papers
Synthesis and Enzymic Activity of 6-Carbethoxy- and 6-Ethoxy-3,7-disubstituted-pyrazolopyrimidines and Related Derivatives as Adenosine Cyclic 3',5'-Phosphate Phosphodiesterase Inhibitors
Springer, Robert H.,Scholten, M. B.,O'Brien, Darrell E.,Novinson, Thomas,Miller, Jon P.,Robins, Roland K.
, p. 235 - 242 (2007/10/02)
A number of 3,7-disubstituted 6-carbethoxypyrazolopyrimidines and 3,7-disubstituted 6-ethoxypyrazolopyrimidines have been prepared and evaluated as adenosine cyclic 3',5'-phosphate (cAMP) phosphodiesterase (PDE) inhibitors vs. the low Km enzyme isolated from beef heart, rabbit lung, and kidney preparations.The results were found to be between 0.5 to 13 times as potent as theophylline as inhibitors of PDE, depending on the tissue source.A number of these PDE inhibitors exhibited significant physiological effects in different animal systems, suggesting it should be possible to obtain selective PDE inhibition in various tissues.Several of these heterocycles were found superior to adenosine in inhibiting ADP-induced platelet aggregation in vitro.
