430424-56-9

Basic information

• Product Name: (E)-3-Hydroxy-2-((E)-2-phenylsulfanyl-1-trifluoromethyl-vinyl)-pent-2-enoic acid ethyl ester
• Synonyms: (E)-3-Hydroxy-2-((E)-2-phenylsulfanyl-1-trifluoromethyl-vinyl)-pent-2-enoic acid ethyl ester
• CAS NO: 430424-56-9
• Molecular Weight: 346.37
• Mol File: 430424-56-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-Hydroxy-2-((E)-2-phenylsulfanyl-1-trifluoromethyl-vinyl)-pent-2-enoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-Hydroxy-2-((E)-2-phenylsulfanyl-1-trifluoromethyl-vinyl)-pent-2-enoic acid ethyl ester(430424-56-9)
• EPA Substance Registry System: (E)-3-Hydroxy-2-((E)-2-phenylsulfanyl-1-trifluoromethyl-vinyl)-pent-2-enoic acid ethyl ester(430424-56-9)

Safety Data

• Hazardous Substances Data: 430424-56-9(Hazardous Substances Data)

Upstream product

• 177272-50-3 1-Bromo-1-phenylsulfanyl-3,3,3-trifluoroprop-1-ene 
• 4949-44-4 ethyl propanoylacetate 

Relevant articles and documents

The regio- and stereoselective addition of carbon nucleophiles to trifluoromethyl phenylsulfanyl acetylene: A novel and expeditious approach to 3-trifluoromethyl furans

A convenient generation of trifluoromethyl phenylsulfanyl acetylene was realized from 2-bromo-1-phenylsulfanyl-3,3,3-trifluoropropene. The reagent was reacted with carbanions to give (1E,3E)-2-trifluoromethylbutadienyl phenyl sulfides regio- and stereoselectively, which underwent intramolecular cyclization in decalin at 190°C or in acetic acid with 1,4-benzoquinone and sodium acetate to afford 3-trifluoromethyl-substituted furans in high yields.