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Deoxyshikonin, a member of the naphthoquinone group, is a naturally occurring chemical compound predominantly found in the roots of the purple gromwell plant, Lithospermum erythrorhizon. Characterized by its red-orange pigment, deoxyshikonin exhibits a range of beneficial properties, including anti-inflammatory, antimicrobial, and antioxidant effects. Its potential applications in medicine and skincare, along with its wound-healing and skin-protective capabilities, make it a valuable compound for further research and development.

43043-74-9

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43043-74-9 Usage

Uses

Used in Skincare Industry:
Deoxyshikonin is used as an active ingredient for its skin-protective and wound-healing properties, contributing to the development of skincare products that promote skin health and recovery.
Used in Pharmaceutical Industry:
Deoxyshikonin is used as a potential therapeutic agent for its demonstrated anticancer properties in preclinical studies, suggesting its efficacy in cancer treatment.
Used in Antimicrobial Applications:
Given its antimicrobial properties, deoxyshikonin is utilized as an agent to combat microbial infections, potentially leading to the creation of new antimicrobial products.
Used in Anti-inflammatory Applications:
Deoxyshikonin is employed as an anti-inflammatory agent, which can be beneficial in the treatment of various inflammatory conditions, thus expanding its use in medicinal formulations.
Used in Antioxidant Formulations:
Capitalizing on its antioxidant properties, deoxyshikonin is used in formulations aimed at neutralizing free radicals and reducing oxidative stress, thereby contributing to overall health and wellness products.

Check Digit Verification of cas no

The CAS Registry Mumber 43043-74-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,4 and 3 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 43043-74:
(7*4)+(6*3)+(5*0)+(4*4)+(3*3)+(2*7)+(1*4)=89
89 % 10 = 9
So 43043-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H16O4/c1-9(2)4-3-5-10-8-13(19)14-11(17)6-7-12(18)15(14)16(10)20/h4,6-8,17-18H,3,5H2,1-2H3

43043-74-9 Well-known Company Product Price

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  • TCI America

  • (D2117)  Deoxyshikonin  >98.0%(HPLC)

  • 43043-74-9

  • 100mg

  • 1,350.00CNY

  • Detail

43043-74-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 5,8-dihydroxy-2-(4-methylpent-3-enyl)naphthalene-1,4-dione

1.2 Other means of identification

Product number -
Other names 11-Deoxyalkannin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:43043-74-9 SDS

43043-74-9Upstream product

43043-74-9Downstream Products

43043-74-9Relevant academic research and scientific papers

Biotransformation of shikonin by human intestinal bacteria

Meselhy, Meselhy R.,Kadota, Shigetoshi,Tsubono, Koji,Hattori, Masao,Namba, Tsuneo

, p. 3081 - 3098 (1994)

The bacterial transformation of shikonin (1) in culture media has been investigated using human intestinal bacteria. Of 24 anaerobes tested, Bacteroides fragilis subsp. thetaotus showed an ability to transform 1 extensively to ten metabolites, five monomers; anhydroalkannin (2), deoxyshikonin (3), cycloshikonin (4), metaboshikonin I (5) and II (6), and five dimers; shikometabolins A (7), B (8), C (9), D (10) and E (11), after anaerobic incubation for 3 days. The structures of these metabolites were determined mainly by 2D-NMR including the INADEQUATE experiment.

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