43043-74-9 Usage
General Description
Deoxyshikonin is a natural chemical compound that belongs to the naphthoquinone group and is primarily found in the roots of Lithospermum erythrorhizon, commonly known as the purple gromwell plant. It is a red-orange pigment with potential anti-inflammatory, antimicrobial, and antioxidant properties. Deoxyshikonin has been extensively studied for its medicinal properties and has been found to possess wound-healing and skin-protective effects, making it a potential candidate for use in skincare and pharmaceutical products. Additionally, it has exhibited anticancer properties in preclinical studies, suggesting its potential as a therapeutic agent for cancer treatment. Overall, deoxyshikonin is a promising compound with various potential applications in the fields of medicine and skincare.
Check Digit Verification of cas no
The CAS Registry Mumber 43043-74-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,4 and 3 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 43043-74:
(7*4)+(6*3)+(5*0)+(4*4)+(3*3)+(2*7)+(1*4)=89
89 % 10 = 9
So 43043-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H16O4/c1-9(2)4-3-5-10-8-13(19)14-11(17)6-7-12(18)15(14)16(10)20/h4,6-8,17-18H,3,5H2,1-2H3
43043-74-9Relevant articles and documents
Biotransformation of shikonin by human intestinal bacteria
Meselhy, Meselhy R.,Kadota, Shigetoshi,Tsubono, Koji,Hattori, Masao,Namba, Tsuneo
, p. 3081 - 3098 (1994)
The bacterial transformation of shikonin (1) in culture media has been investigated using human intestinal bacteria. Of 24 anaerobes tested, Bacteroides fragilis subsp. thetaotus showed an ability to transform 1 extensively to ten metabolites, five monomers; anhydroalkannin (2), deoxyshikonin (3), cycloshikonin (4), metaboshikonin I (5) and II (6), and five dimers; shikometabolins A (7), B (8), C (9), D (10) and E (11), after anaerobic incubation for 3 days. The structures of these metabolites were determined mainly by 2D-NMR including the INADEQUATE experiment.
