430435-76-0

Upstream product

• 88-74-4 2-nitro-aniline 
• 135-02-4 ortho-anisaldehyde 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 1015084-72-6 [CoCl₂(1-(2-methoxybenzyl)-2-(2-methoxyphenyl)-1H-benzimidazole)2] 

Relevant academic research and scientific papers

A copper(II) complex of benzimidazole-based ligand: synthesis, structure, redox aspects and fluorescence properties

Employing 1-(2-methoxybenzyl)-2-(2-methoxyphenyl)-1H-benzimidazole (bpb) as a monodentate ligand, a new greenish-blue copper(II) complex, [Cu(bpb)2(NO3)2] (1a), has been synthesized. 1a has been characterized analytically

Preparation method of 1, 2-substituted benzimidazole compound

The invention discloses a method for synthesizing a series of 1, 2-substituted benzimidazole compounds by using 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIm] [PF6]) as a reaction medium andcarrying out condensation coupling reaction on o-phenyle

Zinc complexes with 1,2-disubstituted benzimidazole ligands: Experimental and theoretical studies in the catalytic cycloaddition of CO2 with epoxides

The synthesis and characterization of four zinc(II) complexes with monodentate 1,2-disubstituted benzimidazole ligands and their catalytic activity in the cycloaddition of CO2 and epoxides are reported. The complexes were characterized by

Method for synthesizing 1,2-disubstituted benzimidazole compounds from 3-hydroxy-2-naphthoic acid assisted with titanocene dichloride

The invention discloses a method for synthesizing 1,2-disubstituted benzimidazole compounds from 3-hydroxy-2-naphthoic acid assisted with titanocene dichloride. According to the method, o-phenylenediamine and aldehyde are used as raw materials, ethanol or

Mesoporous silica supported ytterbium as catalyst for synthesis of 1,2-disubstituted benzimidazoles and 2-substituted benzimidazoles

The benzimidazole ring is an important pharmacophore in contemporary drug discovery. Thus, effort to identifying new compounds containing benzimidazole scaffolds have gained much attention in recent years. In the present study, MCM-41 type mesoporous silica with large pore (l-MSN) supported ytterbium was successfully prepared by wet impregnation method. Among rare earth metal salts, ytterbium triflate has already been widely investigated as a catalyst in organic synthesis but less toxic ytterbium oxide has yet to be explored. Relatively high abundance and low cost of ytterbium with respect to many catalytically active metals (e.g. Pd, Au, Ru, Ir, Pt) offer an opportunity to develop sustainable catalysts for organic conversions. The catalyst has been characterized by various techniques including nitrogen adsorption, FT-IR, TEM, SEM, EDX technique and elemental mapping. The obtained materials exhibit high surface area and a narrow distribution of mesoporosity. The catalytic performance of the Yb@l–MSNs was tested by synthesis of 1,2-disubstituted benzimidazoles and 2-substituted benzimidazoles through the coupling of aldehydes with o-phenylenediamine. The catalyst resulted in excellent yields in short reaction times and the reaction showed tolerance toward both electron-donating and electron-withdrawing functional groups at room temperature. A particularly interesting finding was the solvent selectivity of this reaction; namely, 1,2-disubstituted benzimidazoles generated as major product in water-ethanol, while the 2-substituted benzimidazoles was generated exclusively in non-polar solvents like toluene.

A modern and practical laccase-catalysed route suitable for the synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles

Heterocyclic aromatic compounds containing an imine (C═N) bond such as benzimidazoles and benzothiazoles are important active pharmaceutical ingredients. The synthesis of 2-aryl-1H-benzimidazoles and 2-arylbenzothiazoles in good to excellent yields was ac

Synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles catalysed by ferric ammonium sulfate (NH4Fe(SO4)2) under solvent-free conditions

NH4Fe(SO4)2 was found to be a mild and effective catalyst for the selective synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles under solvent-free conditions.

Lewis acidic ionic liquids of crown ether complex cations: Preparation and applications in organic reactions

A range of Lewis acidic ionic liquids composed of crown ether complex cations were designed, synthesised and characterised by Raman, MS, FT-IR, thermogravimetric differential thermal analysis (TGA-DSC) and elemental analysis. These Lewis acidic ionic liqu

Cobalt manganese oxide nanoparticles as recyclable catalyst for efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles under solvent-free conditions

Cobalt manganese oxide nanocatalyst was synthesized and it was found that it is a highly efficient green catalyst for the synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles under solvent-free conditions. The marked advantages of this method are the si

Nano ZnO catalyzed one-pot synthesis of benzimidazoles from o-phenylenediamine with aldehydes

Nano-ZnO was found to be a highly efficient and reusable heterogeneous catalyst for the one-pot synthesis of substituted benzimidazoles from aromatic aldehydes with o-phenylenediamine in moderate to good yield. The spent catalyst can be easily recovered and reused for five cycles with consistent activity.