43053-63-0

Upstream product

• 141-97-9 ethyl acetoacetate 
• 122334-37-6 4-chloro-N-methoxy-N-methylbenzamide 
• 4111-54-0 lithium diisopropyl amide 
• 4231-70-3 p-chlorobenzoyl-1H-1,2,3-benzotriazole 

Downstream Products

• 170912-90-0 6-(4-Chlorophenyl)-4-hydroxy-3-[(2-phenylethyl)thio]-2H-pyran-2-one 
• 21080-41-1 β-hydroxy-benzenepentanoic acid 
• 6302-55-2 1-(4'-chlorophenyl)-1,3-butanedione 

Relevant academic research and scientific papers

Facile syntheses of 2,2-dimethyl-6-(2-oxoalkyl)-1,3-dioxin-4-ones and the corresponding 6-substituted 4-hydroxy-2-pyrones

A variety of 2,2-dimethyl-6-(2-oxoalkyl)-1,3-dioxin-4-ones 5a-l and the corresponding 6-substituted 4-hydroxy-2-pyrones 3a-l were prepared in high yields under mild reaction conditions by the reaction of 2,2,6-trimethyl-1,3- dioxin-4-one 4 with 1-acylbenz

Pyrone derivatives as protease inhibitors and antiviral agents

The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment