43071-52-9 Usage
Description
2-Acetyl-7-methoxybenzofuran is an organic compound that serves as a building block in the synthesis of various chemical compounds. It is characterized by the presence of an acetyl group at the 2nd position and a methoxy group at the 7th position on a benzofuran ring.
Uses
Used in Pharmaceutical Industry:
2-Acetyl-7-methoxybenzofuran is used as a reagent for the preparation of 2-ethylbenzofuran derivatives, which are potent human uric acid transporter 1 (hURAT1) inhibitors. These inhibitors play a crucial role in the management of hyperuricemia and gout by reducing the levels of uric acid in the body. The development of such inhibitors can lead to the creation of effective treatments for these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 43071-52-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,7 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 43071-52:
(7*4)+(6*3)+(5*0)+(4*7)+(3*1)+(2*5)+(1*2)=89
89 % 10 = 9
So 43071-52-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H10O3/c1-7(12)10-6-8-4-3-5-9(13-2)11(8)14-10/h3-6H,1-2H3
43071-52-9Relevant articles and documents
SYNTHESIS AND APPLICATION OF IMIDAZOLE DERIVATIVES. SYNTHESIS OF (1-METHYL-1H-IMIDAZOL-2-YL)METHANOL DERIVATIVES AND CONVERSION INTO CARBONYL COMPOUNDS
Ohta, Shunsaku,Hayakawa, Satoshi,Nishimura, Kazuko,Okamoto, Masao
, p. 1058 - 1069 (2007/10/02)
(1-methyl-2H-imidazol-2-yl)methanol derivatives ( 4 and 7 ) were prepared by treating carbonyl compounds with 2-lithio-1-methyl-1H-imidazole ( 2 ) or by treating 2-acyl-1H-imidazoles ( 3 ) with organometallic reagents or sodium borohydride.The alcohols ( 4 and 7 ) were convertible into the carbonyl compounds via the corresponding quaternary salts ( 8 and 10 ).The stable (1-methyl-1H-imidazol-2-yl)methanol system, , can be regarded as a masked form of the carbonyl group as well as a synthon of the group.Keywords - (1-methyl-1H-imidazol-2-yl)methanol; 2-acyl-1-methyl-1H-imidazole; carbonyl compound synthesis; β-ketoester; protecting group; latent functionality; symmetric ketone; dihydrojasmone