4308-57-0Relevant academic research and scientific papers
Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs
Zheng, Xing,Zhao, Fei Fei,Liu, Yun Mei,Yao, Xu,Zheng, Zi Tong,Luo, Xing,Liao, Duan Fang
scheme or table, p. 6 - 8 (2011/10/31)
A series of chrysin derivatives were prepared from 2-hydroxyacetophenone, 2,4-dihydroxyacetophenone, 2,4,6-trihydroxy- acetophenone, using modified Baker-Venkataraman transformation. Their anticancer activities in vitro were evaluated by the standard MTT method. The results of biological test showed that some of chrysin derivatives showed stronger anticancer activity than 5-fluorouracil.
