4308-57-0Relevant articles and documents
Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs
Zheng, Xing,Zhao, Fei Fei,Liu, Yun Mei,Yao, Xu,Zheng, Zi Tong,Luo, Xing,Liao, Duan Fang
, p. 6 - 8 (2011/10/31)
A series of chrysin derivatives were prepared from 2-hydroxyacetophenone, 2,4-dihydroxyacetophenone, 2,4,6-trihydroxy- acetophenone, using modified Baker-Venkataraman transformation. Their anticancer activities in vitro were evaluated by the standard MTT method. The results of biological test showed that some of chrysin derivatives showed stronger anticancer activity than 5-fluorouracil.