Novobiocin calcium is a semi-synthetic antibiotic derived from the natural product novobiocin, which is produced by the bacterium Streptomyces spheroides. It is a member of the coumarin family of antibiotics and works by inhibiting bacterial DNA gyrase, an enzyme essential for bacterial DNA replication and transcription. Novobiocin calcium is primarily used to treat infections caused by Gram-positive bacteria, such as Staphylococcus and Streptococcus species. It is administered orally and has a broad-spectrum activity, making it effective against various bacterial strains. However, due to its potential side effects and the emergence of antibiotic resistance, its use is often limited to specific cases where other antibiotics are not suitable or have failed.
The CAS Registry Mumber 4309-70-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,0 and 9 respectively; the second part has 2 digits, 7 and 0 respectively. Calculate Digit Verification of CAS Registry Number 4309-70: (6*4)+(5*3)+(4*0)+(3*9)+(2*7)+(1*0)=80 80 % 10 = 0 So 4309-70-0 is a valid CAS Registry Number.