431-44-7

Basic information

• Product Name: methyl 2,2-dichloro-2-fluoroacetate
• Synonyms: methyl 2,2-dichloro-2-fluoroacetate
• CAS NO: 431-44-7
• Molecular Weight: 160.96
• Mol File: 431-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,2-dichloro-2-fluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,2-dichloro-2-fluoroacetate(431-44-7)
• EPA Substance Registry System: methyl 2,2-dichloro-2-fluoroacetate(431-44-7)

Safety Data

• Hazardous Substances Data: 431-44-7(Hazardous Substances Data)

Upstream product

• 598-99-2 Methyl trichloroacetate 

Downstream Products

• 19302-02-4 ((Z)-2-Chloro-2-fluoro-1-trifluoromethyl-vinyl)-benzene 
• 19302-03-5 trans-α-trifluoromethyl-β,β-fluorochlorostyrene 
• 726-76-1 2,2-dichloro-2-fluoro-1,1-diphenyl-ethanol 
• 19099-57-1 (Chloro-fluoro-methylene)-cyclohexane 
• 1868-91-3 2,2-dichloro-1,1-bis-(4-chloro-phenyl)-2-fluoro-ethanol 
• 174826-64-3 methyl 4-(4-chlorophenyl)-4-cyclopropyl-2-fluorobut-2-enoate 
• 174826-66-5 methyl 4-(4-chlorophenyl)-2-fluoro-4-methylpent-2-enoate 
• 246233-70-5 (Z)-4-(4-Chloro-phenyl)-2-fluoro-5-methyl-hex-2-enoic acid methyl ester 
• 174826-67-6 methyl 4-(4-ethoxyphenyl)-2-fluoro-4-methylpent-2-enoate 
• 246233-62-5 1-(4-chlorophenyl)-1-(2-fluoro-2-(methoxycarbonyl)ethenyl)cyclopropane 
• 246233-63-6 1-(2-Fluoro-2-(methoxycarbonyl)ethenyl)-1-(4-fluorophenyl)cyclopropane 
• 246233-61-4 1-(4-ethoxyphenyl)-1-(2-fluoro-2-methoxycarbonylvinyl)cyclopropane 
• 174826-65-4 methyl 4-cyclopropyl4-(4-ethoxyphenyl)-2-fluorobut-2-enoate 
• 174826-68-7 methyl 2-fluoro4-methyl-4-(4-trifluoromethoxyphenyl)pent-2-enoate 

Relevant articles and documents

Zinc(0)-Copper(I) Chloride Promoted Reaction of Methyl Dichlorofluoroacetate with Carbonyl Compounds. A New Efficient Method for the Synthesis of Methyl (Z)-α-Fluoro-α,β-unsaturated Carboxylates

Methyl dichlorofluoroacetate, easily prepared from methyl trichloroacetate and antimony(III) fluoride, underwent the reductive coupling-elimination raection with carbonyl compounds in the presence of zinc(0), a catalytic amount of copper(I) chloride, acetic anhydride, and molecular sieves to give the corresponding (Z)-α-fluoro-α,β-unsaturated carboxylic acid methyl esters in high yields.