4310-35-4 Usage
Uses
Tridihexethyl Chloride, is an anticholinergic, antimuscarinic and antispasmodic drug.
Brand name
Pathilon (Lederle).
General Description
Tridihexethyl chloride,3-cyclohexyl-3-hydroxy-3-phenylpropyl)triethylammoniumchloride (Pathilon), is a white, bitter, crystalline powderwith a characteristic odor. The compound is freely soluble inwater and alcohol, with aqueous solutions being nearly neutralin reaction. Although this drug, introduced in 1958, has ganglionblockingactivity, its peripheral atropine-like activity predominates;therefore, its therapeutic application has beenbased on the latter activity. It possesses the antispasmodicand the antisecretory activities characteristic of this group,but because of its quaternary character, it is valueless in relievingParkinson syndrome.
Clinical Use
tridihexethyl chloride is useful for adjunctive therapy in a wide varietyof GI diseases, such as peptic ulcer, gastric hyperacidity,and hypermotility and spastic conditions, such as spasticcolon, functional diarrhea, pylorospasm, and other relatedconditions. Because its action is predominantly antisecretory,it is more effective in gastric hypersecretion than in hypermotilityand spasm. It is best administered intravenouslyfor the latter conditions. The side effects usually found with effective anticholinergictherapy occur with the use of this drug. These are drynessof mouth, mydriasis, and such. As with other anticholinergics,care should be exercised when administering the drug topatients with glaucomatous conditions, cardiac decompensation,and coronary insufficiency. It is contraindicated inpatients with obstruction at the bladder neck, prostatic hypertrophy,stenosing gastric and duodenal ulcers, or pyloric orduodenal obstruction.
Check Digit Verification of cas no
The CAS Registry Mumber 4310-35-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,1 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 4310-35:
(6*4)+(5*3)+(4*1)+(3*0)+(2*3)+(1*5)=54
54 % 10 = 4
So 4310-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H36NO.ClH/c1-4-22(5-2,6-3)18-17-21(23,19-13-9-7-10-14-19)20-15-11-8-12-16-20;/h7,9-10,13-14,20,23H,4-6,8,11-12,15-18H2,1-3H3;1H/q+1;/p-1
