43112-62-5Relevant academic research and scientific papers
A Simple Synthesis of 2(3H)-Benzoxazolones using Phenyl Chloroformate
Maleski, Robert J.,Osborne, C. Edward,Cline, Sharon M.
, p. 1937 - 1939 (2007/10/02)
2(3H)-Benzoxazolones 3 can be prepared directly from the corresponding 2-aminophenols and phenyl chloroformate.The intermediate 2-hydroxy phenylcarbamates 2 are formed easily in aqueous alcohol solvent and these are converted rapidly to product, without their isolation, using one equivalent of sodium hydroxide.The synthesis accommodates a wide variety of substituents, including the easily hydrolyzed ethyl ester.
