43126-29-0

Basic information

• Product Name: (E)-megastigma-4,8-diene-3,7-dione
• CAS NO: 43126-29-0
• Molecular Weight: 206.285
• Mol File: 43126-29-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-megastigma-4,8-diene-3,7-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-megastigma-4,8-diene-3,7-dione(43126-29-0)
• EPA Substance Registry System: (E)-megastigma-4,8-diene-3,7-dione(43126-29-0)

Safety Data

• Hazardous Substances Data: 43126-29-0(Hazardous Substances Data)

Usage

General Description

(E)-megastigma-4,8-diene-3,7-dione is a chemical compound that is a key component in the formation of the aroma and flavor of various organisms, including plants and fungi. It is classified as a diketone, which means it contains two ketone functional groups. (E)-megastigma-4,8-diene-3,7-dione is known for its potent odor and is often used in the production of perfumes, flavorings, and fragrances. Some research has suggested that (E)-megastigma-4,8-diene-3,7-dione may also have medicinal properties, including potential anti-inflammatory and anti-cancer effects. It is commonly found in essential oils and has a strong, sweet, and floral scent. Additionally, it is used as a flavoring agent in the food and beverage industry, particularly in the creation of floral and fruity flavors.

Upstream product

• 31162-42-2 4-(1-Hydroxy-4-oxo-2,6,6 trimethylcyclohexyl)-but-3-yn-2-ol 
• 24720-09-0 α-damascone 
• 35734-61-3 3-hydroxymegastigma-5,8-dien-7-one 
• 73126-99-5 (E)-megastigma-5,8-diene-3,7-dione 

Relevant articles and documents

Selective oxygenation of ionones and damascones by fungal peroxygenases

Apocarotenoids are among the most highly valued fragrance constituents, being also appreciated as synthetic building blocks. This work shows the ability of unspecific peroxygenases (UPOs, EC1.11.2.1) from several fungi, some of them being described recently, to catalyze the oxyfunctionalization of α- and β-ionones and α- and β-damascones. Enzymatic reactions yielded oxygenated products such as hydroxy, oxo, carboxy, and epoxy derivatives that are interesting compounds for the flavor and fragrance and pharmaceutical industries. Although variable regioselectivity was observed depending on the substrate and enzyme, oxygenation was preferentially produced at the allylic position in the ring, being especially evident in the reaction with α-ionone, forming 3-hydroxy-α-ionone and/or 3-oxo-α-ionone. Noteworthy were the reactions with damascones, in the course of which some UPOs oxygenated the terminal position of the side chain, forming oxygenated derivatives (i.e., the corresponding alcohol, aldehyde, and carboxylic acid) at C-10, which were predominant in the Agrocybe aegerita UPO reactions, and first reported here.

Butenoyl-cyclohexanones

Use of oxygenated alicyclic compounds, some of which are new, as perfuming and/or flavouring ingredients in the manufacture of perfumes and perfumed products and/or in the preparation of artificial flavours for foodstuffs, animal feeds, beverages, pharmac