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9,10-Didehydro-6-methylergoline-8β-carboxylic acid morpholino ester, commonly known as Methergoline, is a semi-synthetic ergot alkaloid derivative with a wide range of medical applications. It is a potent vasoconstrictor that stimulates smooth muscle tissues, leading to a vasospastic action that aids in the prevention of blood loss.

4314-63-0

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4314-63-0 Usage

Uses

Used in Obstetrics:
9,10-Didehydro-6-methylergoline-8β-carboxylic acid morpholino ester is used as a vasoconstrictor for the management of postpartum hemorrhage. It helps to control excessive bleeding after childbirth by constricting blood vessels, thereby reducing blood loss.
Used in Neurology:
9,10-Didehydro-6-methylergoline-8β-carboxylic acid morpholino ester is used as a treatment for migraines. It works by constricting the blood vessels in the brain, which can help to alleviate the pain and other symptoms associated with migraines.
Used in Gynecology:
9,10-Didehydro-6-methylergoline-8β-carboxylic acid morpholino ester is used as a tocolytic agent to prevent or halt premature labor. It helps to delay the onset of labor by constricting the blood vessels in the uterus, thus maintaining the pregnancy for a longer duration.
Used in Chemical and Biological Research:
9,10-Didehydro-6-methylergoline-8β-carboxylic acid morpholino ester is used as a subject of research for its potential applications in various fields. Its intrinsic properties make it a valuable compound for studying its effects on different biological systems and exploring new therapeutic uses.
Note: While Methergoline has several medical applications, it is important to consider its side effects, such as nausea and hallucinations, and its contraindication in pregnancy due to the risk of inducing abortion.

Check Digit Verification of cas no

The CAS Registry Mumber 4314-63-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,1 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4314-63:
(6*4)+(5*3)+(4*1)+(3*4)+(2*6)+(1*3)=70
70 % 10 = 0
So 4314-63-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H23N3O2/c1-22-12-14(20(24)23-5-7-25-8-6-23)9-16-15-3-2-4-17-19(15)13(11-21-17)10-18(16)22/h2-4,9,11,14,18,21H,5-8,10,12H2,1H3/t14-,18-/m1/s1

4314-63-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [(6aR,9R)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-morpholin-4-ylmethanone

1.2 Other means of identification

Product number -
Other names Lysergic acid morpholide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4314-63-0 SDS

4314-63-0Synthetic route

morpholine
110-91-8

morpholine

lysergic acid-azide; hydrochloride

lysergic acid-azide; hydrochloride

A

4-(6-methyl-9,10-didehydro-ergoline-8α-carbonyl)-morpholine
53543-81-0

4-(6-methyl-9,10-didehydro-ergoline-8α-carbonyl)-morpholine

B

4-(6-methyl-9,10-didehydro-ergoline-8-carbonyl)-morpholine
4314-63-0

4-(6-methyl-9,10-didehydro-ergoline-8-carbonyl)-morpholine

4314-63-0Upstream product

4314-63-0Downstream Products

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