43154-04-7Relevant academic research and scientific papers
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis
Matviiuk, Tetiana,Mori, Giorgia,Lherbet, Christian,Rodriguez, Frédéric,Pasca, Maria Rosalia,Gorichko, Marian,Guidetti, Brigitte,Voitenko, Zoia,Baltas, Michel
, p. 46 - 52 (2014)
In the present paper, we report the synthesis via catalytic Michael reaction and biological results of a series of 3-heteryl substituted pyrrolidine-2,5-dione derivatives as moderate inhibitors against Mycobacterium tuberculosis H37Rv growth. Some of them present also inhibition activities against InhA.
