43156-16-7

Upstream product

• 43155-88-0 3-amine-4-nitrophenyl-[(o-methyl)phenyl]ether 
• 1635-61-6 5-chloro-2-nitroaniline 
• 95-48-7 ortho-cresol 

Downstream Products

• 43155-49-3 methyl 5-<(o-methyl)phenoxy>-2-benzimidazolecarbamate 
• 1205676-95-4 3-{4-[(o-methyl)phenoxy]-1,2-phenylendiamine}-5,6-dimethyl-2-cyclohexenone 
• 243142-72-5 2-methylthio-3H-4-(p-methylphenyl)-7-<(o-methyl)phenoxy>-1,5-benzodiazepine 

Relevant academic research and scientific papers

Efficient synthesis and spectroscopy of 3,3-dimethyl-2,3,4,5,10,11- hexahydro-8-[(o-; and p-methyl)phenoxy]-11-[(o-; and p-substituted)phenyl]-1 H-dibezo-[b,e][1,4]diazepin-1-ones

(Chemical Equation Presented) An easy synthesis of four steps to afforded 12 new derivatives of 3,3-dimethyl-2,3,4,5,10,11-hexahydro-8-[(o-; and p-methyl)phenoxy]-11-[(o-; and p-substituted)phenyl]-1H-dibezo-[b,e][1,4]diazep- in-1-ones IV, 1-12 with potential biological and pharmacological activity as sedative, hypnotic-muscular relaxing, anticonvulsant, and schizophrenia treatment of the central nervous system (CNS). The final products have been obtained with good yields, by condensation and cyclization between 3-{4-[(o-; and p-methyl)phenoxy]-1,2-phenylendiamine}-5,5-dimethyl-2-cyclohexanone III, with the corresponding (o-; and p-R)benzaldehyde. The structure of all derivatives was corroborated by spectroscopy of ir, 1H, and 13C NMR, with bi-dimensional experiments and EI-MS in low and high resolution with collision-induced dissociation experiments (CID).

Synthesis and spectral properties of methyl 5-[(o-, m-, and p-r)- phenoxy]-2-benzimidazolecarbamate

The preparation of eleven novel methyl 5-[(o-, m-, p-R)-phenoxy-2- benzimidazolecarbamates with possible pharmacological activity as anthelmintics is described. The structure of all products was corroborated by it, 1H-nmr, 13C-nmr and mass spectra.