4316-48-7

Basic information

• Product Name: Methyl 4-oxooctanoate
• Synonyms: 4-Ketocaprylic acid methyl ester;4-Oxooctanoic acid methyl ester;Methyl 4-oxooctanoate
• CAS NO: 4316-48-7
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 172.22
• Mol File: 4316-48-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 72 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 0.9786 g/cm3
• CAS DataBase Reference: Methyl 4-oxooctanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-oxooctanoate(4316-48-7)
• EPA Substance Registry System: Methyl 4-oxooctanoate(4316-48-7)

Safety Data

• Hazardous Substances Data: 4316-48-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 40, p. 1676, 1975 DOI: 10.1021/jo00899a046Synthesis, p. 361, 1994

Upstream product

• 110-62-3 pentanal 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 83346-36-5 4,4-bis-(4-hydroxy-phenyl)-octanoic acid 

Relevant articles and documents

Stetter reaction in room temperature ionic liquids and application to the synthesis of haloperidol

Imidazolium-type room temperature ionic liquids (RTILs) have been used for the Stetter reaction, affording the desired 1,4-dicarbonyl compounds in good yields. Thiazolium salts and Et3N are efficient catalysts for this reaction performed in ionic liquid. The possibility to recycle and reuse the solvent has been demonstrated, although it was not possible to recycle the thiazolium catalyst. This method was used in the total synthesis of haloperidol.