431874-77-0Relevant academic research and scientific papers
The bromopentadienyl acrylate approach to himbacine.
Wong, Leon S-M,Sharp, Lisa A,Xavier, Natacha M C,Turner, Peter,Sherburn, Michael S
, p. 1955 - 1957 (2002)
[reaction: see text] The syntheses of 4,4a-didehydrohimbacine and 4,4a-didehydrohimandravine are presented. Key steps include an intramolecular Diels-Alder reaction of a bromopentadienyl acrylate and Suzuki-Miyaura and Stille coupling reactions.
A novel short convergent entry into himbacine derivatives.
Van Cauwenberge, Gunther,Gao, Ling-Jie,Van Haver, Dirk,Milanesio, Marco,Viterbo, Davide,De Clercq, Pierre J
, p. 1579 - 1582 (2007/10/03)
[reaction: see text]. The IMDA reaction of 9 leads with good stereoselectivity to exo-adduct 10b. The functionalized ABC-ring core in 10 is well suited for the convergent synthesis of analogues of himbacine, a naturally occurring M2 selective muscarine re
