4319-56-6

Usage

Uses

Used in Pharmaceutical Industry:
21-HYDROXY-4-PREGNENE-3,20-DIONE 21-GLUCOSIDE is used as a pharmaceutical compound for its potential therapeutic effects. 21-HYDROXY-4-PREGNENE-3,20-DIONE 21-GLUCOSIDE's unique structure may contribute to its ability to modulate various biological pathways, making it a candidate for the development of new drugs targeting specific health conditions.
Used in Nutraceutical Industry:
In the nutraceutical industry, 21-HYDROXY-4-PREGNENE-3,20-DIONE 21-GLUCOSIDE is used as a dietary supplement due to its potential health benefits. 21-HYDROXY-4-PREGNENE-3,20-DIONE 21-GLUCOSIDE may have a role in supporting hormonal balance and overall well-being, although further research is needed to fully understand its effects and establish appropriate dosages.
Used in Cosmetic Industry:
21-HYDROXY-4-PREGNENE-3,20-DIONE 21-GLUCOSIDE may also find application in the cosmetic industry, where it could be utilized for its potential anti-aging and skin health benefits. 21-HYDROXY-4-PREGNENE-3,20-DIONE 21-GLUCOSIDE's ability to interact with various biological pathways may contribute to improved skin elasticity, hydration, and overall appearance.
Used in Agricultural Industry:
In agriculture, 21-HYDROXY-4-PREGNENE-3,20-DIONE 21-GLUCOSIDE could be used as a natural component in the development of plant growth regulators or pesticides. Its unique structure may provide novel mechanisms for enhancing crop growth or protecting plants from pests and diseases.

InChI:InChI=1/C27H40O8/c1-26-9-7-15(29)11-14(26)3-4-16-17-5-6-19(27(17,2)10-8-18(16)26)20(30)13-34-25-24(33)23(32)22(31)21(12-28)35-25/h11,16-19,21-25,28,31-33H,3-10,12-13H2,1-2H3

Upstream product

• 64-85-7 21-Hydroxyprogesterone 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 133-89-1 UDP-glucose 
• 2816-24-2 2-nitrophenyl β-D-glucopyranoside 
• 41092-37-9 21-(tetra-O-acetyl-β-D-glucopyranosyloxy)-pregn-4-ene-3,20-dione 

Relevant academic research and scientific papers

OcUGT1-catalyzing glycodiversification of steroids through glucosylation and transglucosylation actions

Steroidal glycosides are important sources of innovative drugs. The increased diversification of steroidal glycosides will expand the probability of discovering active molecules. It is an efficient approach to diversify steroidal glycosides by using steroidal glycosyltransferases. OcUGT1, a uridine diphosphate-d-glucose (UDP-Glc)-dependent glycosyltransferase from Ornithogalum caudatum, is a multifunctional enzyme, and its glycodiversification potential towards steroids has never been fully explored. Herein, the glycodiversification capability of OcUGT1 towards 25 steroids through glucosylation and transglucosylation reactions were explored. Firstly, each of 25 compounds was glucosylated with UDP-Glc. Under the action of OcUGT1, five steroids (testosterone, deoxycorticosterone, hydrocortisone, estradiol, and 4-androstenediol) were glucosylated to form corresponding mono-glucosides and biosides. Next, OcUGT1-mediated transglucosylation activity of these compounds with another sugar donor ortho-nitrophenyl-β-d-glucopyranoside (oNPGlc) was investigated. Results revealed that the same five steroids could be glucosylated to generate mono-glucosides and biosides by OcUGT1 through transglucosylation reactions. These data indicated that OcUGT1-assisted glycodiversification of steroids could be achieved through glucosylation and transglucosylation reactions. These results provide a way to diversify steroidal glycosides, which lays the foundation for the increase of the probability of obtaining active lead compounds.