4319-68-0

Usage

Uses

Used in Pharmaceutical Industry:
4'-Deoxyphlorizin is used as an inhibitor of the glucose transport system for its potential role in managing and treating diabetes. By inhibiting the glucose transport system, it may help regulate blood sugar levels and provide a therapeutic approach to diabetes management.
Used in Research and Development:
In the field of research and development, 4'-Deoxyphlorizin serves as a valuable compound for studying the mechanisms of glucose transport and its regulation. This knowledge can be applied to develop new drugs and therapies for diabetes and other related conditions.
Used in Drug Design and Development:
4'-Deoxyphlorizin's ability to inhibit the glucose transport system makes it a promising candidate for drug design and development. Researchers can use 4'-Deoxyphlorizin as a starting point to create new drugs that target glucose transport, potentially leading to more effective treatments for diabetes and other glucose-related disorders.

InChI:InChI=1/C21H24O9/c22-10-16-18(26)19(27)20(28)21(30-16)29-15-3-1-2-13(24)17(15)14(25)9-6-11-4-7-12(23)8-5-11/h1-5,7-8,16,18-24,26-28H,6,9-10H2

Upstream product

• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 699-83-2 2,6-dihydroxylacetophenone 
• 23141-00-6 2',6'-dihydroxyacetophenone 2'-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside) 
• 4397-53-9 p-benzyloxybenzaldehyde 

Downstream Products

• 156728-88-0 1-[2-((4aR,6S,7R,8R,8aS)-7,8-Dihydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-6-hydroxy-phenyl]-3-(4-hydroxy-phenyl)-propan-1-one 
• 217634-71-4 Acetic acid (4aR,6S,7R,8S,8aR)-7-acetoxy-6-{2-[3-(4-acetoxy-phenyl)-propionyl]-3-hydroxy-phenoxy}-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 217634-72-5 Acetic acid (4aR,6S,7R,8S,8aR)-7-acetoxy-6-{3-hydroxy-2-[3-(4-hydroxy-phenyl)-propionyl]-phenoxy}-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 

Relevant academic research and scientific papers

Na+-glucose cotransporter inhibitors as antidiabetics. I. Synthesis and pharmacological properties of 4'-dehydroxyphlorizin derivatives based on a new concept

Based on our new concept that inhibitors of the Na+-glucose cotransporter (SGLT) would be useful as antidiabetics, 4'-dehydroxyphlorizin derivatives 1a-f were designed, synthesized, and examined for various pharmacological properties related to