431981-73-6

Upstream product

• 431990-36-2 2-[(1RS,4E,6E)-10-(tert-butyldimethylsilanyloxy)-1-(tert-butyldiphenylsilanyloxy)-4-methyldeca-4,6-dienyl]thiophene 

Downstream Products

• 431990-53-3 tert-butyl-[(1RS,4E,6E)-4-methyl-1-thiophen-2-yl-10-(3,4,5-trimethoxybenzyloxy)deca-4,6-dienyloxy]diphenylsilane 
• 431990-56-6 (4E,6E,10RS)-10-(tert-butyldiphenylsilanyloxy)-7-methyl-10-thiophen-2-yldeca-4,6-dienal 

Relevant academic research and scientific papers

Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A

Structure-activity relationship analysis of synthetic analogues of curacin A revealed the lack of activity of traditional heterocyclic replacements of the thiazoline ring or cyclopropyl analogues of the core diene segment. The significance of the C(3)-C(4