43199-18-4Relevant academic research and scientific papers
Carboxylate binding in polar solvents using pyridylguanidinium salts
Fitzmaurice, Richard J.,Gaggini, Francesca,Srinivasan, Natarajan,Kilburn, Jeremy D.
, p. 1706 - 1714 (2008/02/10)
A series of thiourea and guanidinium derivatives have been prepared and their ability to bind a carboxylate group has been investigated. Guanidinium 33, featuring two additional amides and a pyridine moiety, proved to be the most potent carboxylate bindin
BETA-STRAND MIMETICS AND METHOD RELATING THERETO
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Page 78-79; 80, (2008/06/13)
Conformationally constrained compounds which mimic the secondary structure of ?-strand regions of biologically active peptides and proteins are disclosed. Such ?-strand mimetic structures have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the ?-strand mimetic structures of this invention are also disclosed as well as methods for screening the same to identify biologically active members.
