43200-96-0

Basic information

• Product Name: ZOPICLONE N-OXIDE
• Synonyms: ZOPICLONE N-OXIDE; RP 2975;1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester;Zopiclone N-Oxide (Mixture of diastereomers);RP 29753;Zopiclone N-Oxide (Eszopiclone Impurity A) (Mixture of Diastereomers);Zopiclone N-Oxide (Eszopiclone Impurity A) ;4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester 4-oxide
• CAS NO: 43200-96-0
• Molecular Formula: C17H17ClN6O4
• Molecular Weight: 404.81
• EINECS: 200-659-6
• Product Categories: Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Heterocycles;Impurities;Isotopically Labeled Pharmaceutical Reference Standard
• Mol File: 43200-96-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: >140°C (dec.)
• Flash Point: 9℃
• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Soni
• PKA: 4.92±0.20(Predicted)
• CAS DataBase Reference: ZOPICLONE N-OXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ZOPICLONE N-OXIDE(43200-96-0)
• EPA Substance Registry System: ZOPICLONE N-OXIDE(43200-96-0)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: UN1230 - class 3 - PG 2 - Methanol
• WGK Germany: 1
• Hazardous Substances Data: 43200-96-0(Hazardous Substances Data)

Usage

Chemical Properties

Off-White to Pale Beige Solid

Uses

Different sources of media describe the Uses of 43200-96-0 differently. You can refer to the following data:
1. A metabolite of Zopiclone
2. Eszopiclone impurity A.

General Description

Zopiclone N-oxide is a primary, active metabolite of zopiclone in urine as well as a major pharmaceutical impurity of zopiclone known as eszopiclone impurity A. The parent drug, zopiclone, is a non-benzodiazepine hypnotic sold under the trade names Imovane?and ZImovane?and is used in the treatment of insomnia.

InChI:InChI=1/C17H17ClN6O4/c1-24(27)8-6-22(7-9-24)17(26)28-16-14-13(19-4-5-20-14)15(25)23(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3