432003-61-7Relevant academic research and scientific papers
Indole macrocycles formed by diindolylmethane ring closure
Purwono, Bambang,Kumar, Naresh,Black, David StC
, (2022/02/14)
Indole containing macrocyclic compounds can be formed from suitable diindolyl diesters and diamides by acidcatalysed reaction with formaldehyde to generate a 2,2′-linkage in the ring closure step. The alternative protocol in which macrocyclisation is attempted by lactone or lactam formation from starting 2,2′- diindolylmethane systems was unsuccessful in our examples.
